Neurofilaments are obligate heteropolymers in vivo

MK Lee, Z Xu, PC Wong, DW Cleveland - The Journal of cell biology, 1993 - rupress.org
Neurofilaments (NFs), composed of three distinct subunits NF-L, NF-M, and NF-H, are
neuron-specific intermediate filaments present in most mature neurons. Using DNA …

cdc2-like kinase from rat spinal cord specifically phosphorylates KSPXK motifs in neurofilament proteins: isolation and characterization.

KT Shetty, WT Link, HC Pant - Proceedings of the National …, 1993 - National Acad Sciences
A protein kinase that phosphorylates a specific KSP sequence [K (S/T) PXK], which is
abundant in high molecular weight neurofilament (NF) proteins, was identified and isolated …

Structural features in the heptad substructure and longer range repeats of two-stranded α-fibrous proteins

JF Conway, DAD Parry - International journal of biological macromolecules, 1990 - Elsevier
Considerable sequence data have been collected from the intermediate filament proteins
and other α-fibrous proteins including myosin, tropomyosin, paramyosin, desmoplakin and …

Requirement of heavy neurofilament subunit in the development of axons with large calibers

GA Elder, VL Friedrich Jr, C Kang, P Bosco… - The Journal of cell …, 1998 - rupress.org
Neurofilaments (NFs) are prominent components of large myelinated axons. Previous
studies have suggested that NF number as well as the phosphorylation state of the COOH …

[HTML][HTML] Molecular characterization of a mammalian smooth muscle myosin light chain kinase.

PJ Gallagher, BP Herring, SA Griffin, JT Stull - Journal of Biological …, 1991 - Elsevier
A 5.6-kilobase cDNA clone has been isolated which includes the entire coding region for the
myosin light chain kinase from rabbit uterine tissue. This cDNA, expressed in COS cells …

Phosphorylation of bovine neurofilament proteins by protein kinase FA (glycogen synthase kinase 3)

RJ Guan, BS Khatra, JA Cohlberg - Journal of Biological Chemistry, 1991 - Elsevier
A highly purified preparation of protein kinase FA (where FA is the activating factor for
phosphatase 1)/glycogen synthase kinase 3 from rabbit muscle readily phosphorylated …

Neurofilament mRNA is reduced in Parkinson's disease substantia nigra pars compacta neurons

WD Hill, M Arai, JA Cohen… - Journal of Comparative …, 1993 - Wiley Online Library
Lewy bodies are filamentous neuronal inclusions characteristic of Parkinson's disease, and
neurofilament triplet proteins are the major components of the filaments in Lewy bodies …

A molecular mechanism for the induction of neurofilament bundling by aluminum ions

JF Leterrier, D Langui, A Probst… - Journal of …, 1992 - Wiley Online Library
Al induces neurofibrillary tangles in the perikaryon of neurons in vivo and in culture. The
effect of Al ions complexed with maltol, a plant‐derived ligand of Al, on purified …

Structural properties of neurofilament sidearms: sequence-based modeling of neurofilament architecture

R Chang, Y Kwak, Y Gebremichael - Journal of molecular biology, 2009 - Elsevier
Neurofilaments (NFs) are essential cytoskeletal filaments that impart mechanical integrity to
nerve cells. They are assembled from three distinct molecular mass proteins that bind to …

Neurofilaments are intrinsic determinants of axonal caliber

NA Muma, PN Hoffman - Micron, 1993 - Elsevier
Neurofilaments (NFs) are intrinsic determinants of axonal caliber in large-caliber myelinated
nerve fibers. Axonal caliber is influenced by the number of NFs in the axon (axonal NF …