White matter makes up about fifty percent of the human brain. Maturation of white matter
accompanies biological development and undergoes the most dramatic changes during …

Hypomyelinating leukodystrophies constitute a subset of genetic white matter disorders
characterized by a primary lack of myelin deposition. Most patients with severe …

Myelin water imaging is a quantitative neuroimaging technique that provides the myelin
water fraction (MWF), a metric highly specific to myelin content, and the intra-/extra-cellular …

Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer
with water between the wraps. The measurement of damage to the myelin sheaths, the …

Leukodystrophies constitute a large and heterogeneous group of genetic diseases primarily
affecting the white matter of the central nervous system. Different disorders target different …

Background Neurofilaments are cytoskeletal proteins that are detectable in the blood after
neuroaxonal injury. Multiple sclerosis (MS) disease progression, greater lesion volume, and …

We provide a rich multi-contrast microstructural MRI dataset acquired on an ultra-strong
gradient 3T Connectom MRI scanner comprising 5 repeated sets of MRI microstructural …

Update on myelin imaging in neurological syndromes : Current Opinion in Neurology Update
on myelin imaging in neurological syndromes : Current Opinion in Neurology Log in or …

Background White matter myelination is a crucial process of CNS maturation. The purpose
of this study was to validate the T1w/T2w mapping technique for brain myelination …

Diffusion-weighted imaging studies have repeatedly shown that white matter correlates with
reading throughout development. However, the neurobiological interpretation of this …