Automation and computer-assisted planning for chemical synthesis

Y Shen, JE Borowski, MA Hardy, R Sarpong… - Nature Reviews …, 2021 - nature.com
The molecules of today—the medicines that cure diseases, the agrochemicals that protect
our crops, the materials that make life convenient—are becoming increasingly sophisticated …

High‐throughput experimentation and computational freeway lanes for accelerated battery electrolyte and interface development research

A Benayad, D Diddens, A Heuer… - Advanced Energy …, 2022 - Wiley Online Library
The timely arrival of novel materials plays a key role in bringing advances to society, as the
pace at which major technological breakthroughs take place is usually dictated by the …

Autonomous optimization of non-aqueous Li-ion battery electrolytes via robotic experimentation and machine learning coupling

A Dave, J Mitchell, S Burke, H Lin, J Whitacre… - Nature …, 2022 - nature.com
Developing high-energy and efficient battery technologies is a crucial aspect of advancing
the electrification of transportation and aviation. However, battery innovations can take years …

From platform to knowledge graph: evolution of laboratory automation

J Bai, L Cao, S Mosbach, J Akroyd, AA Lapkin, M Kraft - JACS Au, 2022 - ACS Publications
High-fidelity computer-aided experimentation is becoming more accessible with the
development of computing power and artificial intelligence tools. The advancement of …

Advances in microfluidics: technical innovations and applications in diagnostics and therapeutics

G Aubry, HJ Lee, H Lu - Analytical Chemistry, 2023 - ACS Publications
Microfluidics describes the study of systems that operate fluids at miniature scales, often in
microchannels. It is powerful in scaling down biological experiments by many orders of …

A review of microfluidic-based mixing methods

Z Li, B Zhang, D Dang, X Yang, W Yang… - Sensors and Actuators A …, 2022 - Elsevier
Microfluidic-based mixing methods have aroused increasing attention due to their
tremendous potential in bio-related and materials science fields. Achieving mixing based on …

Ready, set, flow! Automated continuous synthesis and optimization

CP Breen, AMK Nambiar, TF Jamison, KF Jensen - Trends in Chemistry, 2021 - cell.com
Synthetic chemistry provides access to advanced materials that facilitate innovation in key
industries such as medicine, energy, and agriculture. Automation is poised to challenge the …

Toward machine learning-enhanced high-throughput experimentation

NS Eyke, BA Koscher, KF Jensen - Trends in Chemistry, 2021 - cell.com
Recent literature suggests that the fields of machine learning (ML) and high-throughput
experimentation (HTE) have separately received considerable attention from chemists and …

Unlocking the potential of high-throughput experimentation for electrochemistry with a standardized microscale reactor

J Rein, JR Annand, MK Wismer, J Fu, JC Siu… - ACS Central …, 2021 - ACS Publications
Organic electrochemistry has emerged as an enabling and sustainable technology in
modern organic synthesis. Despite the recent renaissance of electrosynthesis, the broad …

Autonomous closed-loop mechanistic investigation of molecular electrochemistry via automation

H Sheng, J Sun, O Rodríguez, BB Hoar… - Nature …, 2024 - nature.com
Electrochemical research often requires stringent combinations of experimental parameters
that are demanding to manually locate. Recent advances in automated instrumentation and …