Aldehyde sources, metabolism, molecular toxicity mechanisms, and possible effects on human health

PJ O'Brien, AG Siraki, N Shangari - Critical reviews in toxicology, 2005 - Taylor & Francis
Aldehydes are organic compounds that are widespread in nature. They can be formed
endogenously by lipid peroxidation (LPO), carbohydrate or metabolism ascorbate …

Molecular viral oncology of hepatocellular carcinoma

TM Block, AS Mehta, CJ Fimmel, R Jordan - Oncogene, 2003 - nature.com
Hepatocellular carcinoma (HCC) is the fifth most common cancer, but the third leading
cause of cancer death, in the world, with more than 500 000 fatalities annually. The major …

Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics

AM Calcagno, CD Salcido, JP Gillet… - Journal of the …, 2010 - academic.oup.com
Background Cancer stem cells are presumed to have virtually unlimited proliferative and self-
renewal abilities and to be highly resistant to chemotherapy, a feature that is associated with …

Glycosylation and liver cancer

A Mehta, H Herrera, T Block - Advances in cancer research, 2015 - Elsevier
Liver cancer is the fifth most common cancer, but the second leading cause of cancer death,
in the world, with more than 700,000 fatalities annually. The major etiology of liver cancer is …

Proteome analysis of hepatocellular carcinoma by two-dimensional difference gel electrophoresis: novel protein markers in hepatocellular carcinoma tissues

W Sun, B Xing, Y Sun, X Du, M Lu, C Hao, Z Lu… - Molecular & cellular …, 2007 - ASBMB
Hepatocellular carcinoma (HCC) is a highly malignant tumor, and chronic infection with
hepatitis B virus is one of its major risk factors. To identify the proteins involved in HCC …

Overexpression of alpha enolase in hepatitis C virus‐related hepatocellular carcinoma: association with tumor progression as determined by proteomic analysis

M Takashima, Y Kuramitsu, Y Yokoyama, N Iizuka… - …, 2005 - Wiley Online Library
To identify proteins that could be molecular targets for diagnosis and treatment of hepatitis C
virus‐related hepatocellular carcinoma (HCV‐related HCC), we used a proteomic approach …

Proteomic differences between hepatocellular carcinoma and nontumorous liver tissue investigated by a combined gel-based and label-free quantitative proteomics …

DA Megger, T Bracht, M Kohl, M Ahrens… - Molecular & Cellular …, 2013 - ASBMB
Proteomics-based clinical studies have been shown to be promising strategies for the
discovery of novel biomarkers of a particular disease. Here, we present a study of …

Accurate qualitative and quantitative proteomic analysis of clinical hepatocellular carcinoma using laser capture microdissection coupled with isotope-coded affinity …

C Li, Y Hong, YX Tan, H Zhou, JH Ai, SJ Li… - Molecular & Cellular …, 2004 - ASBMB
Laser capture microdissection (LCM) is a powerful tool that enables the isolation of specific
cell types from tissue sections, overcoming the problem of tissue heterogeneity and …

Proteomics in biomarker discovery and drug development

QY He, JF Chiu - Journal of cellular biochemistry, 2003 - Wiley Online Library
Proteomics is a research field aiming to characterize molecular and cellular dynamics in
protein expression and function on a global level. The introduction of proteomics has been …

Enhancement of vitality and activity of a plant growth-promoting bacteria (PGPB) by atmospheric pressure non-thermal plasma

SH Ji, JS Kim, CH Lee, HS Seo, SC Chun, J Oh… - Scientific reports, 2019 - nature.com
The inconsistent vitality and efficiency of plant growth promoting bacteria (PGPB) are
technical limitations in the application of PGPB as biofertilizer. To improve these …