Ecological and demographic factors can significantly shape the evolution of microbial
populations both directly and indirectly, as when changes in the effective population size …

Bacteria evolve as a result of mutations and acquisition of foreign DNA by recombination
processes. A growing body of evidence suggests that mutation and recombination rates are …

Biased mutation spectra are pervasive, with wide variation in the magnitude of mutational
biases that influence genome evolution and adaptation. How do such diverse biases …

Mutation accumulation experiments followed by whole-genome sequencing have revealed
that, for several bacterial species, the rate of base-pair substitutions (BPSs) is not constant …

Bacteria lose and gain repair genes as they evolve. Here, we investigate the consequences
of gain and loss of 11 DNA repair genes across a broad range of bacteria. Using …

Abstract The Context-dependent Mutation Analysis Package and Visualization Software
(CDMAP/CDVIS) is an automated, modular toolkit used for the analysis and visualization of …

Mutations play a pivotal role as a driver of genome evolution in organisms across the tree of
life. However, site-specific mutation rates appear to have a non-uniform mutation rate and …

Mutation accumulation experiments followed by whole-genome sequencing have revealed
that for 27 several bacterial species the rate of base-pair substitutions is not constant across …