Acute kidney injury (AKI) is common in the critically ill. Inadequate renal medullary tissue
oxygenation has been linked to its pathogenesis. Moreover, renal medullary tissue hypoxia …

Acute kidney injury (AKI) is a common clinical syndrome with limited treatment options and
high mortality rates. Proximal tubular epithelial cells (PTECs) play a key role in AKI …

Background Hypotension during induction of anaesthesia is associated with organ injury.
Continuous arterial pressure monitoring might help reduce hypotension. We tested the …

Background Iron sulfide nanomaterials have been successfully employed as therapeutic
agents for bacterial infection therapy and catalytic-ferroptosis synergistic tumor therapy due …

In this pre-specified sub-study of the POISE-3 trial, we examined the effect of a perioperative
hypotension-avoidance strategy versus a hypertension-avoidance strategy on the risk of …

Background Acute kidney injury (AKI) is a frequent adverse outcome following liver
transplantation (LT) with a multifactorial etiology. It is critical to identify modifiable risk factors …

Serotonin 3 receptor antagonists, a commonly used drug for preventing postoperative
nausea and vomiting, have recently been reported to decrease the incidence of hypotension …

Acute kidney injury (AKI) is a common but fatal complication after cardiac surgery. In the
absence of effective treatments, the identification and modification of risk factors has been a …

Background: The prevalence of obesity is high. Bariatric surgery is an effective treatment for
severe obesity; however, the induction phase of anesthesia in these patients poses a risk of …

Objectives To determine if the administration of norepinephrine to patients recovering from
on-pump cardiac surgery is associated with changes in urinary oxygen tension (PO 2), an …