Neuroinflammation in schizophrenia: the role of nuclear factor kappa B

CE Murphy, AK Walker, CS Weickert - Translational psychiatry, 2021 - nature.com
Neuroinflammation, particularly in the dorsolateral prefrontal cortex, is well-established in a
subset of people with schizophrenia, with significant increases in inflammatory markers …

The relationship between inflammatory biomarkers and cognitive dysfunction in patients with schizophrenia: A systematic review and meta-analysis

SR Patlola, G Donohoe, DP McKernan - Progress in Neuro …, 2023 - Elsevier
Background Schizophrenia is a complex psychiatric disorder that includes positive and
negative symptoms but also debilitating cognitive deficits. Current pharmacological …

High prevalence and adverse health effects of loneliness in community-dwelling adults across the lifespan: role of wisdom as a protective factor

EE Lee, C Depp, BW Palmer, D Glorioso… - International …, 2019 - cambridge.org
Objectives: This study of loneliness across adult lifespan examined its associations with
sociodemographics, mental health (positive and negative psychological states and traits) …

Differences in gut microbiome composition between persons with chronic schizophrenia and healthy comparison subjects

TT Nguyen, T Kosciolek, Y Maldonado, RE Daly… - Schizophrenia …, 2019 - Elsevier
Intestinal microbiome and gut-brain axis have been receiving increasing attention for their
role in the regulation of brain/behavior and possible biological basis of psychiatric disorders …

Socioeconomic status and inflammation: a meta-analysis

KA Muscatell, SN Brosso, KL Humphreys - Molecular psychiatry, 2020 - nature.com
Socioeconomic status (SES), often conceptualized as income, education, or occupation, is
associated with risk for disease morbidity and psychopathology. Recent research has …

Cytokines and C-reactive protein alterations with respect to cognitive impairment in schizophrenia and bipolar disorder: a systematic review

B Misiak, B Stańczykiewicz, K Kotowicz… - Schizophrenia …, 2018 - Elsevier
Background The aim of this article was to perform a systematic review of studies
investigating the association between peripheral levels of cytokines and C-reactive protein …

Peripheral inflammatory and neurotrophic biomarkers of cognitive impairment in schizophrenia: a meta-analysis

E Bora - Psychological medicine, 2019 - cambridge.org
BackgroundSchizophrenia is associated with significant cognitive impairment. However, the
pathophysiological mechanisms underlying cognitive dysfunction in schizophrenia remain …

Multi-omics of human plasma reveals molecular features of dysregulated inflammation and accelerated aging in schizophrenia

A Campeau, RH Mills, T Stevens, LA Rossitto… - Molecular …, 2022 - nature.com
Schizophrenia is a devastating psychiatric illness that detrimentally affects a significant
portion of the worldwide population. Aging of schizophrenia patients is associated with …

C-reactive protein as a biomarker for major depressive disorder?

L Orsolini, S Pompili, S Tempia Valenta, V Salvi… - International journal of …, 2022 - mdpi.com
The etiopathogenesis of depression is not entirely understood. Several studies have
investigated the role of inflammation in major depressive disorder. The present work aims to …

The relationship between immune and cognitive dysfunction in mood and psychotic disorder: a systematic review and a meta-analysis

M Morrens, C Overloop, V Coppens, E Loots… - Molecular …, 2022 - nature.com
Background In psychotic and mood disorders, immune alterations are hypothesized to
underlie cognitive symptoms, as they have been associated with elevated blood levels of …