History of mankind is regarded as struggle against infectious diseases. Rather than
observing the withering away of bacterial diseases, antibiotic resistance has emerged as a …

An overuse of antibiotics both in human and animal health and as growth promoters in
farming practices has increased the prevalence of antibiotic resistance in bacteria. Antibiotic …

Microbial species rarely exist in isolation. In naturally occurring microbial systems there is
strong evidence for a positive relationship between species diversity and productivity of …

There is almost a century since discovery of penicillin by Alexander Fleming, a century of
enthusiasm, abuse, facing development of antibiotic-resistance and clear conclusion that the …

Microcins are an understudied and poorly characterized class of antimicrobial peptides.
Despite the existence of only 15 examples, all identified from the Enterobacteriaceae …

Predictability is a fundamental requirement in biological engineering. As we move to
building coordinated multicellular systems, the potential for such systems to display chaotic …

A commensal microbial community is established in the mammalian gut during its
development, and these organisms protect the host against pathogenic invaders. The …

Background Antimicrobial peptides are very primitive innate defense molecules of almost all
organisms, from microbes to mammalians and vascular seed-bearing plants. Antimicrobial …

Antibiotic-resistant pathogens have become a major public health problem worldwide. New
discoveries and strategies as regards antibiotic drug development are urgently in need for …

Antimicrobial peptides are a promising alternative to traditional antibiotics, but their utility is
limited by high production costs and poor bioavailability profiles. Bacterial production and …