ML218 modulates calcium binding protein, oxidative stress, and inflammation during ischemia-reperfusion brain injury in mice

P Sharma, B Sharma, S Ghildiyal… - European Journal of …, 2024 - Elsevier
Cerebral ischemia disrupts calcium homeostasis in the brain causing excitotoxicity, oxidative
stress, inflammation, and neuronal cell apoptosis. During ischemic conditions, T-type …

Selective inhibition of T-type calcium channel preserves ischemic pre-conditioning mediated neuroprotection during cerebral ischemia reperfusion injury in diabetic …

P Sharma, B Sharma, H Kharkwal, S Ghildiyal… - Metabolic Brain …, 2025 - Springer
Ischemic preconditioning (IPC) provides ischemic tolerance and neuroprotection during
cerebral ischemia reperfusion (CI/R) injury. Diabetes abolishes the beneficial effects of …

[HTML][HTML] Brivaracitam Ameliorates Increased Inflammation, Oxidative Stress, and Acetylcholinesterase Activity in Ischemic Mice

C Deval, P Sharma, B Sharma… - Clinical …, 2024 - pmc.ncbi.nlm.nih.gov
Objective Cerebral ischemia is a medical condition that occurs due to poor supply of blood
in the brain. Reperfusion being savage further exaggerates the tissue injury causing …

[HTML][HTML] Dopamine receptor agonist pramipexole exerts neuroprotection on global cerebral ischemia/reperfusion injury by inhibiting ferroptosis

X Kang, W Wang, Y Zuo, Y Wang, L Zhang… - Journal of Stroke and …, 2025 - Elsevier
Objective To explore the mechanism of dopamine receptor agonist pramipexole in exerting
neuroprotection on global cerebral ischemia/reperfusion injury (GCI/R). Material and method …

Montelukast Ameliorates 2K1C-Hypertension Induced Endothelial Dysfunction and Associated Vascular Dementia

S Gupta, P Singh, B Sharma - Current Hypertension Reviews, 2024 - ingentaconnect.com
Background: Declined kidney function associated with hypertension is a danger for cognitive
deficits, dementia, and brain injury. Cognitive decline and vascular dementia (VaD) are …

Neuroprotective Effect of Morinda citrifolia on Behavioural and Biochemical Deficits in PTZ-induced Kindled Mice

M Ali, P Singh, L Singh, RK Pandey… - … Current Drug Targets …, 2023 - ingentaconnect.com
Introduction: Epilepsy is a group of chronic neurological disorders characterized by seizures.
Kindling, a chronic epileptic mouse model, was used to explore the epileptogenic …

[PDF][PDF] Neuroprotective Effect of Chlorogenic Acid against Pentylenetetrazol Induced Kindled Epilepsy in Mice

A Singh, L Singh, R Pandey, P Singh, M Ali… - Int. J. Drug Deliv …, 2023 - researchgate.net
Background: Epilepsy is a group of chronic neurological disorders characterized by
seizures. Kindling, a chronic epileptic mouse model that was used to explore the …

An update on phytoconstituents and pharmacological importance of Asparagus racemosus

D Meher, M Singh, B Meher - Journal of Applied Pharmaceutical …, 2024 - japtronline.com
Background: Asparagus racemosus (family: Liliaceae), is a well-researched traditional or
ancient medicine in the Siddha, Ayurveda, and Unani systems. It is commonly known as …

[PDF][PDF] Remote Limb Ischemic Postconditioning Ameliorated Microglia-Mediated Inflammation Against Cerebral Ischemia/Reperfusion through Modulating Microglial …

D Huang, L Zhang, J Zhong, Y Zou, G Yuan, Z Wang - 2021 - scholar.archive.org
Accumulating researches have indicated that remote limb ischemic postconditioning (RIPC)
mediates neuroprotection by inhibition inflammatory response against cerebral …