Clostridium difficile infection: epidemiology, diagnosis and understanding transmission

JSH Martin, TM Monaghan, MH Wilcox - … reviews Gastroenterology & …, 2016 - nature.com
Clostridium difficile infection (CDI) continues to affect patients in hospitals and communities
worldwide. The spectrum of clinical disease ranges from mild diarrhoea to toxic megacolon …

Diagnosis of Clostridium difficile infection: an ongoing conundrum for clinicians and for clinical laboratories

BD Carey-Ann, KC Carroll - Clinical microbiology reviews, 2013 - Am Soc Microbiol
Clostridium difficile is a formidable nosocomial and community-acquired pathogen, causing
clinical presentations ranging from asymptomatic colonization to self-limiting diarrhea to …

Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for …

LC McDonald, DN Gerding, S Johnson… - Clinical infectious …, 2018 - academic.oup.com
Triptolide (TP), a traditional Chinese medicine, has been reported to be effective in the
treatment of autoimmune diseases and exerting antineoplastic activity in several human …

Overdiagnosis of Clostridium difficile infection in the molecular test era

CR Polage, CE Gyorke, MA Kennedy… - JAMA internal …, 2015 - jamanetwork.com
Importance Clostridium difficileis a major cause of health care–associated infection, but
disagreement between diagnostic tests is an ongoing barrier to clinical decision making and …

Re: Burden of Clostridium difficile Infection in the United States

FC Lessa, LC McDonald… - The New England …, 2015 - ncbi.nlm.nih.gov
Banaei and colleagues express concern that Clostridium difficile infection (CDI) may be over
diagnosed using PCR given that in their study only a third of patients had clinically …

Differences in outcome according to Clostridium difficile testing method: a prospective multicentre diagnostic validation study of C difficile infection

TD Planche, KA Davies, PG Coen… - The Lancet infectious …, 2013 - thelancet.com
Summary Background Diagnosis of Clostridium difficile infection is controversial because of
many laboratory methods, compounded by two reference methods. Cytotoxigenic culture …

Emerging technologies for the clinical microbiology laboratory

BW Buchan, NA Ledeboer - Clinical microbiology reviews, 2014 - Am Soc Microbiol
In this review we examine the literature related to emerging technologies that will help to
reshape the clinical microbiology laboratory. These topics include nucleic acid amplification …

Strategies to prevent Clostridium difficile infections in acute care hospitals: 2014 update

ER Dubberke, P Carling, R Carrico… - Infection Control & …, 2014 - cambridge.org
Previously published guidelines are available that provide comprehensive
recommendations for detecting and preventing healthcare-associated infections (HAIs). The …

Clostridioides difficile: diagnosis and treatments

B Guery, T Galperine, F Barbut - Bmj, 2019 - bmj.com
Clostridioides difficile (formerly Clostridium) is a major cause of healthcare associated
diarrhea, and is increasingly present in the community. Historically, C difficile infection was …

Strategies to prevent Clostridioides difficile infections in acute-care hospitals: 2022 Update

LK Kociolek, DN Gerding, R Carrico… - Infection Control & …, 2023 - cambridge.org
Objective Previously published guidelines provided comprehensive recommendations for
detecting and preventing healthcare-associated infections (HAIs). The intent of this …