[PDF][PDF] Transcriptomic and Proteomic Characterization of the Immune Response to Elective Spinal Reconstructive Surgery: Impact of Aging and Comparisons with the …

JW Bonaroti, M Ozel, T Chen, JL Darby… - Journal of the …, 2023 - journals.lww.com
BACKGROUND: Major surgery triggers trauma-like stress responses linked to age, surgery
duration, and blood loss, resembling polytrauma. This similarity suggests elective surgery as …

Systemic inflammation and neuroimmunity in surgical trauma

M Hildenborg - 2024 - openarchive.ki.se
Tissue injury due to surgery or trauma initiates the release of damage associated molecular
patterns (DAMPs), which in turn triggers a cascade of immune cell activation and the release …