There has been a significant progress in our understanding of the molecular mechanisms by
which calcium (Ca2+) ions mediate various types of cardiac arrhythmias. A growing list of …

Purpose Genetic testing has advanced significantly since the publication of the 2011
HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the …

Providing therapies tailored to each patient is the vision of precision medicine, enabled by
the increasing ability to capture extensive data about individual patients. In this position …

Aims Catecholaminergic polymorphic ventricular tachycardia (CPVT) and short QT
syndrome (SQTS) are inherited arrhythmogenic disorders that can cause sudden death …

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a stress‐induced cardiac
channelopathy that has a high mortality in untreated patients. Our understanding has grown …

Aims The term idiopathic ventricular fibrillation (IVF) describes survivors of unexplained
cardiac arrest (UCA) without a specific diagnosis after clinical and genetic testing. Previous …

Background Genetic testing following sudden cardiac death (SCD) is currently guided by
autopsy findings, despite the inherent challenges of autopsy examination and mounting …

Background: Genetic variants in calsequestrin-2 (CASQ2) cause an autosomal recessive
form of catecholaminergic polymorphic ventricular tachycardia (CPVT), although isolated …

Long QT syndrome, short QT syndrome, Brugada syndrome and catecholaminergic
polymorphic ventricular tachycardia are inherited primary electrical disorders that …

Aims Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an ion
channelopathy characterized by ventricular arrhythmia during exertion or stress. Mutations …