Antibiotic-resistant bacteria that are difficult or impossible to treat are becoming increasingly common and are causing a global health crisis. Antibiotic resistance is encoded by several …
D Du, Z Wang, NR James, JE Voss, E Klimont… - Nature, 2014 - nature.com
The capacity of numerous bacterial species to tolerate antibiotics and other toxic compounds arises in part from the activity of energy-dependent transporters. In Gram-negative bacteria …
Polymyxin antibiotics are increasingly being used as last-line therapeutic options against a number of multidrug resistant bacteria. These antibiotics show strong bactericidal activity …
L Daury, F Orange, JC Taveau, A Verchere… - Nature …, 2016 - nature.com
Tripartite multidrug efflux systems of Gram-negative bacteria are composed of an inner membrane transporter, an outer membrane channel and a periplasmic adaptor protein. They …
Resistant bacterial infections are a major health problem in many parts of the world. The major commercial antibiotic classes often fail to combat common bacteria. Although …
A Neuberger, D Du, BF Luisi - Research in microbiology, 2018 - Elsevier
Efflux pumps are membrane proteins which contribute to multi-drug resistance. In Gram- negative bacteria, some of these pumps form complex tripartite assemblies in association …
J Song, J Zhou, L Zhang, R Li - Microorganisms, 2020 - mdpi.com
In recent years, the role of mitochondria in pathogenic fungi in terms of azole resistance and fungal pathogenicity has been a rapidly developing field. In this review, we describe the …
JW Handing, SA Ragland, UV Bharathan… - Frontiers in …, 2018 - frontiersin.org
The mucosal inflammatory response to Neisseria gonorrhoeae (Gc) is characterized by recruitment of neutrophils to the site of infection. Gc survives exposure to neutrophils by …
Gram-negative bacteria utilize a diverse array of multidrug transporters to pump toxic compounds out of the cell. Some transporters, together with periplasmic membrane fusion …