Targeting autophagy, oxidative stress, and ER stress for neurodegenerative disease treatment

Y Esmaeili, Z Yarjanli, F Pakniya, E Bidram… - Journal of Controlled …, 2022 - Elsevier
Protein homeostasis is a vital process for cell function and, therefore, disruption of the
molecular mechanisms involved in this process, such as autophagy, may contribute to …

Ochratoxin A: Toxicity, oxidative stress and metabolism

Y Tao, S Xie, F Xu, A Liu, Y Wang, D Chen… - Food and Chemical …, 2018 - Elsevier
Ochratoxin A (OTA) is a widespread mycotoxin commonly found as a corn contaminant. It
has been shown to be nephrotoxic, hepatotoxic, teratogenic and immunotoxic to several …

Exploring the osteogenic potential of chitosan-quercetin bio-conjugate: In vitro and in vivo investigations in osteoporosis models

Y Li, V Selvaraj, S Saravanan, SS Abullais… - International Journal of …, 2024 - Elsevier
Anti-osteoporotic agents are clinically employed to improve bone health and prevent
osteoporotic fractures. In the current study, we investigated the potential of chitosan …

Ochratoxin A-induced nephrotoxicity: Up-to-date evidence

CS Khoi, JH Chen, TY Lin, CK Chiang… - International journal of …, 2021 - mdpi.com
Ochratoxin A (OTA) is a mycotoxin widely found in various foods and feeds that have a
deleterious effect on humans and animals. It has been shown that OTA causes multiorgan …

Mycotoxins and oxidative stress: where are we?

EO Da Silva, A Bracarense… - World Mycotoxin …, 2018 - wageningenacademic.com
Mycotoxins are the most common contaminants of food and feed worldwide and are
considered an important risk factor for human and animal health. Oxidative stress occurs in …

Nanoparticles as a solution for eliminating the risk of mycotoxins

P Horky, S Skalickova, D Baholet, J Skladanka - Nanomaterials, 2018 - mdpi.com
Mycotoxins are toxic secondary metabolites produced by certain filamentous fungi. The
occurrence of mycotoxins in food and feed causes negative health impacts on both humans …

Ameliorative effect of chitosan nanoparticles against carbon tetrachloride-induced nephrotoxicity in Wistar rats

YA Nomier, S Alshahrani, M Elsabahy… - Pharmaceutical …, 2022 - Taylor & Francis
Context Chitosan is a biocompatible polysaccharide that has been widely exploited in
biomedical and drug delivery applications. Objective This study explores the renoprotective …

Protective effect of quercetin on kidney diseases: From chemistry to herbal medicines

YQ Chen, HY Chen, QQ Tang, YF Li, XS Liu… - Frontiers in …, 2022 - frontiersin.org
Kidney injuries may trigger renal fibrosis and lead to chronic kidney disease (CKD), but
effective therapeutic strategies are still limited. Quercetin is a natural flavonoid widely …

Enhancing the potential preclinical and clinical benefits of quercetin through novel drug delivery systems

R Khursheed, SK Singh, S Wadhwa, M Gulati… - Drug discovery today, 2020 - Elsevier
Highlights•Pharmacological activities and molecular targets of quercetin.•Mechanistic
pathways of quercetin for treating different diseases.•Formulation strategies for improving …

[HTML][HTML] Protective effect of curcumin on ochratoxin A–induced liver oxidative injury in duck is mediated by modulating lipid metabolism and the intestinal microbiota

SS Zhai, D Ruan, YW Zhu, MC Li, H Ye, WC Wang… - Poultry Science, 2020 - Elsevier
Curcumin has antioxidant functions, regulates the intestinal microbial composition, and
alleviates mycotoxin toxicity. The present study aimed to explore whether curcumin could …