Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …

Fibroblasts are important cells for the support of homeostatic tissue function. In inflammatory
diseases such as rheumatoid arthritis and inflammatory bowel disease, fibroblasts take on …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial
inflammation, pannus formation, and bone and cartilage damage. It has a high disability …

The high level of reactive oxygen species (ROS) in the rheumatoid arthritis (RA)
microenvironment (RAM) and its persistent inflammatory nature can promote damage to …

Control of excessive mitochondrial oxidative stress could provide new targets for both
preventive and therapeutic interventions in the treatment of chronic inflammation or any …

Abstract Ethnopharmacological relevance Qi-Sai-Er-Sang-Dang-Song Decoction (QSD, ཆུ་
སེར་ སེང་ ལྡེང་ སུམ་ ཐང་།), a Tibetan classical herbal formula, is commonly used in …

Angiogenesis plays a key role in the pathological process of inflammation and invasion of
the synovium, and primarily drives the progression of rheumatoid arthritis (RA). Recent …

Secreted frizzled-related protein 1 (SFRP1) is a member of secretory glycoprotein SFRP
family. As a primitive gene regulating cell growth, development and transformation, SFRP1 …

Plant microRNAs (miRNA) are regularly consumed orally along with diet, gaining attention
for their RNA-based drug potential because of their ability to regulate mammalian gene …

Objective The purpose of this work is to investigate how the Rho family of GTPases A (RhoA)
mediates the pathogenesis of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS) …