The TIM (T cell/transmembrane, immunoglobulin, and mucin) gene family plays a critical role
in regulating immune responses, including allergy, asthma, transplant tolerance …

Flaviviruses enter host cells by endocytosis initiated when the virus particles interact with
cell surface receptors. The current model suggests that flaviviruses use at least two different …

The role of B cells in anti-tumour immunity is still debated and, accordingly,
immunotherapies have focused on targeting T and natural killer cells to inhibit tumour …

Background Circulating biomarkers are associated with the development of coronary heart
disease (CHD) and its complications by reflecting pathophysiological pathways and/or …

T cell Ig domain and mucin domain protein 1 (TIM-1) is a costimulatory molecule that
regulates immune responses by modulating CD4+ T cell effector differentiation. However …

The T cell immunoglobulin mucin (TIM) proteins regulate T cell activation and tolerance.
Here we showed that TIM-4 is expressed on human and mouse macrophages and dendritic …

Phagocytes such as macrophages and dendritic cells (DCs) engulf apoptotic cells to
maintain peripheral immune tolerance. However, the mechanism for the recognition of dying …

T cell/transmembrane, Ig, and mucin (TIM) proteins, identified using a congenic mouse
model of asthma, critically regulate innate and adaptive immunity. TIM-1 and TIM-4 are …

The transmembrane protein Tim-3 has been shown to negatively regulate T-cell-dependent
immune responses and was recently demonstrated to be associated with the phenomenon …

A variety of both RNA and DNA viruses envelop their capsids in a lipid bilayer. One of the
more recently appreciated benefits this envelope is incorporation of phosphatidylserine …