An involvement of oxidative stress in endoplasmic reticulum stress and its associated diseases

B Bhandary, A Marahatta, HR Kim… - International journal of …, 2012 - mdpi.com
The endoplasmic reticulum (ER) is the major site of calcium storage and protein folding. It
has a unique oxidizing-folding environment due to the predominant disulfide bond formation …

OXPHOS mutations and neurodegeneration

WJH Koopman, F Distelmaier, JAM Smeitink… - The EMBO …, 2013 - embopress.org
Mitochondrial oxidative phosphorylation (OXPHOS) sustains organelle function and plays a
central role in cellular energy metabolism. The OXPHOS system consists of 5 multisubunit …

Antioxidant activities of rapeseed peptides produced by solid state fermentation

R He, X Ju, J Yuan, L Wang, AT Girgih… - Food Research …, 2012 - Elsevier
In this study, rapeseed peptides (RPs) were prepared by solid state fermentation with
Bacillus subtilis followed by evaluation of peptide antioxidant activities (scavenging of …

Characterization of apela, a novel endogenous ligand of apelin receptor, in the adult heart

Á Perjés, T Kilpiö, J Ulvila, J Magga, T Alakoski… - Basic research in …, 2016 - Springer
The G protein-coupled apelin receptor regulates important processes of the cardiovascular
homeostasis, including cardiac development, cardiac contractility, and vascular tone. Most …

X-ROS signaling in the heart and skeletal muscle: stretch-dependent local ROS regulates [Ca2+] i

BL Prosser, RJ Khairallah, AP Ziman, CW Ward… - Journal of molecular and …, 2013 - Elsevier
X-ROS signaling is a novel redox signaling pathway that links mechanical stress to changes
in [Ca2+] i. This pathway is activated rapidly and locally within a muscle cell under …

Role of thyroid hormones-induced oxidative stress on cardiovascular physiology

MLB Arcos - Biochimica et Biophysica Acta (BBA)-General Subjects, 2022 - Elsevier
Thyroid hormones (THs) play an essential role in the maintenance of cardiovascular
homeostasis and are involved in the modulation of cardiac contractility, heart rate, diastolic …

Activation of intracellular matrix metalloproteinase-2 by reactive oxygen–nitrogen species: Consequences and therapeutic strategies in the heart

AL Jacob-Ferreira, R Schulz - Archives of biochemistry and biophysics, 2013 - Elsevier
Reactive oxygen–nitrogen species play important roles in physiological and pathological
processes in the heart. This review will focus on the activation of matrix metalloproteinases …

Estrogen and estrogen receptors in cardiovascular oxidative stress

PA Arias-Loza, M Muehlfelder, T Pelzer - Pflügers Archiv-European …, 2013 - Springer
The cardiovascular system of a premenopausal woman is prepared to adapt to the
challenges of increased cardiac output and work load that accompany pregnancy. Thus, it is …

Ca2+ mishandling and cardiac dysfunction in obesity and insulin resistance: Role of oxidative stress

K Carvajal, J Balderas-Villalobos, MD Bello-Sanchez… - Cell calcium, 2014 - Elsevier
Obesity and insulin resistance (IR) are strongly connected to the development of subclinical
cardiac dysfunction and eventually can lead to heart failure, which is the main cause of …

L‐3‐n‐butylphthalide protects rats' cardiomyocytes from ischaemia/reperfusion‐induced apoptosis by affecting the mitochondrial apoptosis pathway

YG Wang, Y Li, CY Wang, JW Ai, XY Dong… - Acta …, 2014 - Wiley Online Library
Aims This study investigated the role of L‐3‐n‐Butylphthalide (NBP) in cardiac protection.
Methods The left anterior descending coronary arteries (LAD) of the rats were occluded for …