1001 lights: luciferins, luciferases, their mechanisms of action and applications in chemical analysis, biology and medicine

ZM Kaskova, AS Tsarkova, IV Yampolsky - Chemical Society Reviews, 2016 - pubs.rsc.org
Bioluminescence (BL) is a spectacular phenomenon involving light emission by live
organisms. It is caused by the oxidation of a small organic molecule, luciferin, with molecular …

Multi‐level convergence of complex traits and the evolution of bioluminescence

ES Lau, TH Oakley - Biological Reviews, 2021 - Wiley Online Library
Evolutionary convergence provides natural opportunities to investigate how, when, and why
novel traits evolve. Many convergent traits are complex, highlighting the importance of …

[PDF][PDF] The Expanding Toolbox of In Vivo Bioluminescent Imaging

T Xu, D Close, W Handagama, E Marr, G Sayler… - Frontiers in …, 2016 - frontiersin.org
In vivo bioluminescent imaging (BLI) permits the visualization of engineered
bioluminescence from living cells and tissues to provide a unique perspective toward the …

Coelenterazine-dependent luciferases as a powerful analytical tool for research and biomedical applications

VV Krasitskaya, EE Bashmakova, LA Frank - International Journal of …, 2020 - mdpi.com
The functioning of bioluminescent systems in most of the known marine organisms is based
on the oxidation reaction of the same substrate—coelenterazine (CTZ), catalyzed by …

Shining light on the secreted luciferases of marine copepods: Current knowledge and applications

SV Markova, MD Larionova… - Photochemistry and …, 2019 - Wiley Online Library
Copepod luciferases—a family of small secretory proteins of 18.4–24.3 kD a, including a
signal peptide—are responsible for bright secreted bioluminescence of some marine …

Coelenterazine-dependent luciferases

SV Markova, ES Vysotski - Biochemistry (Moscow), 2015 - Springer
Bioluminescence is a widespread natural phenomenon. Luminous organisms are found
among bacteria, fungi, protozoa, coelenterates, worms, molluscs, insects, and fish. Studies …

Development and characterization of a novel luciferase based cytotoxicity assay

H Matta, R Gopalakrishnan, S Choi, R Prakash… - Scientific Reports, 2018 - nature.com
A simple, accurate, sensitive and robust assay that can rapidly and specifically measure the
death of target cells would have applications in many areas of biomedicine and particularly …

[HTML][HTML] Light emission miracle in the sea and preeminent applications of bioluminescence in recent new biotechnology

S Sharifian, A Homaei, R Hemmati, K Khajeh - Journal of Photochemistry …, 2017 - Elsevier
Bioluminescence is referred to the light emission by a living organism due to a specific
biochemical reaction. This interesting feature of the organisms could highly influences …

Miniaturization of bright light-emitting luciferase ALuc: picALuc

Y Ohmuro-Matsuyama, T Furuta, H Matsui… - ACS Chemical …, 2022 - ACS Publications
Luciferases are widely used as sensitive reporters in various fields ranging from basic
biology to medical diagnosis, public health, and food inspection. Scientists have isolated …

Near-infrared fluorescent protein and bioluminescence-based probes for high-resolution in vivo optical imaging

DK Tiwari, M Tiwari, T Jin - Materials Advances, 2020 - pubs.rsc.org
In the last few years, high-resolution near-infrared (NIR) optical imaging has become an
indispensable modality for non-invasive visualization of deep tissues both in fundamental …