Molecular biomarkers of progression in non-muscle-invasive bladder cancer—beyond conventional risk stratification

M Olislagers, FC de Jong, VC Rutten… - Nature Reviews …, 2024 - nature.com
The global incidence of bladder cancer is more than half a million diagnoses each year.
Bladder cancer can be categorized into non-muscle-invasive bladder cancer (NMIBC) …

Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight

CD Hurst, G Cheng, FM Platt, MAA Castro… - Cell Reports …, 2021 - cell.com
Understanding the molecular determinants that underpin the clinical heterogeneity of non-
muscle-invasive bladder cancer (NMIBC) is essential for prognostication and therapy …

Predictive biomarkers of response to bacillus Calmette‐Guérin immunotherapy and bacillus Calmette‐Guérin failure for non‐muscle invasive bladder cancer

Z Wang, WZ So, KY Loh, YK Lim… - … Journal of Urology, 2022 - Wiley Online Library
Within the heterogeneous population of patients with bacillus Calmette‐Guérin failure, there
are clear differences in prognosis and therapy with regard to the timeline when bacillus …

A paclitaxel-hyaluronan conjugate (ONCOFID-PB™) in patients with BCG-unresponsive carcinoma in situ of the bladder: a dynamic assessment of the tumor …

A Tosi, B Parisatto, E Gaffo, S Bortoluzzi… - Journal of Experimental & …, 2024 - Springer
Background The intravesical instillation of the paclitaxel-hyaluronan conjugate ONCOFID-
PB™ in patients with bacillus Calmette-Guérin (BCG)-unresponsive bladder carcinoma in …

The bladder microbiota is not significantly altered by intravesical BCG therapy

V Heidrich, ACH Mariotti, LT Inoue, EM Coser… - … Oncology: Seminars and …, 2024 - Elsevier
Introduction Bladder microbiota dysbiosis has been associated with several urological
disorders. However, dysbiosis markers in bladder cancer have not been identified and little …

Will the use of biomarkers improve bladder cancer radiotherapy delivery?

AA Solanki, BP Venkatesulu, JA Efstathiou - Clinical Oncology, 2021 - Elsevier
Advances in the field of cancer biology and molecular techniques have led to a better
understanding of the molecular underpinnings driving cancer development and outcomes …

Mechanisms and Biomarkers of Response to BCG and Chemotherapy in Bladder Cancer

H Bahlburg, PC Black - Biology of Bladder Cancer: From Molecular …, 2025 - Springer
Almost 50 years after first use, instillation therapy with attenuated strains of Mycobacterium
bovis (Bacillus Calmette-Guérin, BCG) is still the gold standard in the treatment of high-risk …

[HTML][HTML] Emerging biomarkers in metastatic urothelial carcinoma: tumour mutational burden, PD-L1 expression and APOBEC polypeptide-like signature in a patient …

MM Queiroz, ZS de Souza, ABL Gongora… - …, 2021 - ncbi.nlm.nih.gov
Immunotherapy has recently been incorporated into the treatment guidelines for metastatic
urothelial carcinoma. Nevertheless, the role of prognostic and predictive biomarkers in this …

Proceedings from the SIU B2B Uro-Oncology: GU Cancers Triad Virtual Meeting; Bladder Cancer

A Masson-Lecomte - Société Internationale d'Urologie Journal, 2023 - siuj.org
The 4th Bench-to-Bedside Uro-Oncology: GU Cancers Triad Meeting, organized in
conjunction with the 42nd Annual Congress of the Société Internationale d'Urologie, was …

[HTML][HTML] Emerging biomarkers in metastatic urothelial carcinoma: tumour mutational burden, PD-L1 expression and apolipoprotein B mRNA editing catalytic (APOBEC …

MM Queiroz, ZS de Souza, ABL Gongora… - 2021 - ecancer.org
Immunotherapy has recently been incorporated into the treatment guidelines for metastatic
urothelial carcinoma. Nevertheless, the role of prognostic and predictive biomarkers in this …