Abstract Background In Europe cardiovascular disease (CVD) is responsible for 3.9 million
deaths (45% of deaths), being ischaemic heart disease, stroke, hypertension (leading to …

Periodontitis is a complex disease:(a) various causative factors play a role simultaneously
and interact with each other; and (b) the disease is episodic in nature, and bursts of disease …

The oral mucosa remains an understudied barrier tissue. This is a site of rich exposure to
antigens and commensals, and a tissue susceptible to one of the most prevalent human …

INTRODUCTION Mucosal barrier sites are continuously exposed to diverse environmental
stimuli, and the fine-tuning of mucosal tissue–specific immune responses is key to …

Periodontal diseases comprise a wide range of inflammatory conditions that affect the
supporting structures of the teeth (the gingiva, bone and periodontal ligament), which could …

Periodontal diseases and dental caries are the most common diseases of humans and the
main cause of tooth loss. Both diseases can lead to nutritional compromise and negative …

Matrix metalloproteinase‐8 is a promising candidate biomarker for oral fluid (gingival
crevicular fluid, peri‐implant sulcular fluid and saliva) and mouthrinse chair‐side/point‐of …

Dental caries and periodontitis account for a vast burden of morbidity and healthcare
spending, yet their genetic basis remains largely uncharacterized. Here, we identify self …

Studies of the genetics underlying inflammatory bowel diseases have increased our
understanding of the pathways involved in both ulcerative colitis and Crohn's disease and …

The oral mucosa is a primary barrier site and a portal for entry of microbes, food, and
airborne particles into the gastrointestinal tract. Nonetheless, mucosal immunity at this …