A comprehensive review of the health perspectives of resveratrol

A Rauf, M Imran, HAR Suleria, B Ahmad, DG Peters… - Food & function, 2017 - pubs.rsc.org
Many natural products present in our diet, including flavonoids, can prevent the progression
of cancer and other diseases. Resveratrol, a natural polyphenol present in various fruits and …

Cadmium as a testicular toxicant: A Review

JK Bhardwaj, H Panchal, P Saraf - Journal of Applied …, 2021 - Wiley Online Library
Cadmium (Cd) is a toxic heavy metal with no known biological functions in the human body.
Due to a considerably long biological half‐life and very low rate of excretion, accumulation …

Cadmium, organ toxicity and therapeutic approaches: a review on brain, kidney and testis damage

M Rinaldi, A Micali, H Marini, EB Adamo… - Current medicinal …, 2017 - ingentaconnect.com
Background: Cadmium (Cd) is a heavy metal particularly hazardous for human health, as it
is highly diffused and, therefore, a ubiquitous environmental toxicant. In fact, in the general …

Diacerein downregulates NLRP3/Caspase-1/IL-1β and IL-6/STAT3 pathways of inflammation and apoptosis in a rat model of cadmium testicular toxicity

AA Fouad, AM Abdel-Aziz, AAH Hamouda - Biological Trace Element …, 2020 - Springer
The potential gonadal protective effect of diacerein (DCN) and its underlying mechanisms
were studied in a rat model of cadmium-induced testicular toxicity. The rats received DCN …

Cadmium-induced apoptosis through reactive oxygen species-mediated mitochondrial oxidative stress and the JNK signaling pathway in TM3 cells, a model of mouse …

S Wang, X Ren, X Hu, L Zhou, C Zhang… - Toxicology and applied …, 2019 - Elsevier
Cadmium (Cd) is a heavy metal that widely exists in the environment and industry, and
which causes serious damages to reproductive system. Recent studies have reported that …

Heavy metal exposure: molecular pathways, clinical implications, and protective strategies

H Koyama, T Kamogashira, T Yamasoba - Antioxidants, 2024 - mdpi.com
Heavy metals are often found in soil and can contaminate drinking water, posing a serious
threat to human health. Molecular pathways and curation therapies for mitigating heavy …

Selenium ameliorates cadmium-induced mouse leydig TM3 cell apoptosis via inhibiting the ROS/JNK/c-jun signaling pathway

X Ren, S Wang, C Zhang, X Hu, L Zhou, Y Li… - … and environmental safety, 2020 - Elsevier
Despite the well-known acknowledgement of both the toxicity of cadmium (Cd) and the
ameliorative effect of selenium (Se), the mechanism of the protective effect of selenium on …

Mechanisms of phytoremediation by resveratrol against cadmium toxicity

B Mognetti, F Franco, C Castrignano, P Bovolin… - Antioxidants, 2024 - mdpi.com
Cadmium (Cd) toxicity poses a significant threat to human health and the environment due
to its widespread occurrence and persistence. In recent years, considerable attention has …

Nutraceuticals: a new challenge against cadmium-induced testicular injury

HR Marini, A Micali, G Squadrito, D Puzzolo, J Freni… - Nutrients, 2022 - mdpi.com
Cadmium (Cd) is a widespread heavy metal and a ubiquitous environmental toxicant. For
the general population, the principal causes of Cd exposure are cigarette smoking, air …

A flavonoid-rich extract from bergamot juice, alone or in association with curcumin and resveratrol, shows protective effects in a murine model of cadmium-induced …

N Ferlazzo, A Micali, HR Marini, J Freni, G Santoro… - Pharmaceuticals, 2021 - mdpi.com
It is known that cadmium damages testis structure and functionality. We examined the effects
of nutraceuticals such as a flavonoid-rich extract of bergamot juice (BJe), alone or in …