Bioactive synthetic polymers

K Jung, N Corrigan, EHH Wong, C Boyer - Advanced Materials, 2022 - Wiley Online Library
Synthetic polymers are omnipresent in society as textiles and packaging materials, in
construction and medicine, among many other important applications. Alternatively, natural …

Synthesis of imidazolium-based poly (ionic liquids) with diverse substituents and their applications in dispersive solid-phase extraction

AH Mohamed, NA Noorhisham, K Bakar, N Yahaya… - Microchemical …, 2022 - Elsevier
Imidazolium-based poly (ionic liquids)(PILs) belong to a subclass of polyelectrolytes
characterised by a combination of a series of intrinsic ionic liquids features, spatial …

Different insight into amphiphilic PEG-PLA copolymers: influence of macromolecular architecture on the micelle formation and cellular uptake

C Garofalo, G Capuano, R Sottile, R Tallerico… - …, 2014 - ACS Publications
One constrain in the use of micellar carriers as drug delivery systems (DDSs) is their low
stability in aqueous solution. In this study “tree-shaped” copolymers of general formula …

Molecular structure of poly (methyl methacrylate) surface. i. Combination of interface-sensitive infrared–visible sum frequency generation, molecular dynamics …

H Zhu, KC Jha, RS Bhatta, M Tsige, A Dhinojwala - Langmuir, 2014 - ACS Publications
The chemical composition and molecular structure of polymeric surfaces are important in
understanding wetting, adhesion, and friction. Here, we combine interface-sensitive sum …

Impact of charge correlation, chain rigidity, and chemical specific interactions on the behavior of weak polyelectrolytes in solution

A Tagliabue, L Izzo, M Mella - The Journal of Physical Chemistry …, 2019 - ACS Publications
In this work, we performed titration simulations of weak linear polyelectrolytes via the Monte
Carlo method and the constant pH ensemble aiming to understand how polyelectrolyte …

Block copolymer stereoregularity and its impact on polymeric micellar nanodrug delivery

H Soleymani Abyaneh, MR Vakili… - Molecular …, 2017 - ACS Publications
Stereoregularity of polymers is known to influence their physicochemical and functional
properties in the bulk form. Recent studies have also provided evidence for the effect of …

P (HPMA)-block-P (LA) copolymers in paclitaxel formulations: polylactide stereochemistry controls micellization, cellular uptake kinetics, intracellular localization and …

M Barz, A Armiñán, F Canal, F Wolf, K Koynov… - Journal of controlled …, 2012 - Elsevier
In order to explore the influence of polymer microstructure and stereochemistry in biological
settings, the synthesis, micellization, cellular fate and the use in paclitaxel formulations of …

Monte Carlo study of the effects of macroion charge distribution on the ionization and adsorption of weak polyelectrolytes and concurrent counterion release

M Mella, A Tagliabue, L Mollica, L Izzo - Journal of colloid and interface …, 2020 - Elsevier
Hypothesis Adsorption of weak polyelectrolytes onto charged nanoparticles, and concurrent
effects such as spatial partitioning of ions may be influenced by details of the polyelectrolyte …

Modulation of ionization and structural properties of weak polyelectrolytes due to 1D, 2D, and 3D confinement

M Mella, L Izzo - Journal of Polymer Science Part B: Polymer …, 2017 - Wiley Online Library
What is the impact of reducing the space available to molecules onto their properties is a
fundamental question for capillary systems, molecular biology and transport, protein and …

Tacticity effects on conformational structure and hydration of poly-(methacrylic acid) in aqueous solutions-a molecular dynamics simulation study

AK Gupta, U Natarajan - Molecular Simulation, 2016 - Taylor & Francis
The influence of tacticity on chain dimensions, backbone and side-group conformational
states and relaxation dynamics, intermolecular hydrogen bonding and its relaxation …