The role of metabolomics in current concepts of organ preservation

M Kvietkauskas, V Zitkute, B Leber, K Strupas… - International journal of …, 2020 - mdpi.com
In solid organ transplantation (Tx), both survival rates and quality of life have improved
dramatically over the last few decades. Each year, the number of people on the wait list …

Barriers and advances in kidney preservation

C Steichen, S Giraud, D Bon, B Barrou… - BioMed research …, 2018 - Wiley Online Library
Despite the fact that a significant fraction of kidney graft dysfunctions observed after
transplantation is due to ischemia‐reperfusion injuries, there is still no clear consensus …

Effects of oxygen during long-term hypothermic machine perfusion in a porcine model of kidney donation after circulatory death

LH Venema, A Brat, C Moers, NA't Hart, RJ Ploeg… - …, 2019 - journals.lww.com
Background. Hypothermic machine perfusion (HMP) has become standard care in many
center's to preserve kidneys donated after circulatory death (DCD). Despite a significant …

The effects of oxygenation on ex vivo kidneys undergoing hypothermic machine perfusion

K Patel, TB Smith, DAH Neil, A Thakker… - …, 2019 - journals.lww.com
Background Supplemental oxygenation of the standard hypothermic machine perfusion
(HMP) circuit has the potential to invoke favorable changes in metabolism, optimizing …

Metabolic differences between cold stored and machine perfused porcine kidneys: A 1H NMR based study

J Nath, TB Smith, K Patel, SR Ebbs, A Hollis… - Cryobiology, 2017 - Elsevier
Hypothermic machine perfusion (HMP) and static cold storage (SCS) are the two methods
used to preserve deceased donor kidneys prior to transplant. This study seeks to …

The use of porcine corrosion casts for teaching human anatomy

L Eberlova, V Liska, H Mirka, Z Tonar, S Haviar… - Annals of Anatomy …, 2017 - Elsevier
In teaching and learning human anatomy, anatomical autopsy and prosected specimens
have always been indispensable. However, alternative methods must often be used to …

13C glucose labelling studies using 2D NMR are a useful tool for determining ex vivo whole organ metabolism during hypothermic machine perfusion of kidneys

J Nath, T Smith, A Hollis, S Ebbs, SW Canbilen… - Transplantation …, 2016 - Springer
Background The aim of this study is to determine the feasibility of using nuclear magnetic
resonance (NMR) tracer studies (13 C-enriched glucose) to detect ex vivo de novo …

[HTML][HTML] Perfusate metabolomics content and expression of tubular transporters during human kidney graft preservation by hypothermic machine perfusion

Q Faucher, H Alarcan, FL Sauvage, L Forestier… - …, 2022 - journals.lww.com
Background. Ischemia-related injury during the preimplantation period impacts kidney graft
outcome. Evaluating these lesions by a noninvasive approach before transplantation could …

Metabolomics—a powerful tool in livestock research

M Ashokan, E Rana, K Sneha, C Namith… - Animal …, 2023 - Taylor & Francis
Abstract Advancements in the Nuclear Magnetic Resonance (NMR) and Mass Spectrometry
(MS) along with recent developments in omics sciences have resulted in a better …

Salivary and urinary metabolome analysis for pre-puberty-related biomarkers identification in porcine

G Goudet, L Nadal-Desbarats, C Douet, J Savoie… - animal, 2019 - cambridge.org
Estrus synchronization is important for optimal management of gilt reproduction in pig farms.
Hormonal treatments, such as synthetic progestogens, are used on a routine basis, but there …