For many years it has been known that plants perform rapid long-distance signalling using
classical action potentials that have impacts on diverse processes in plants. Plants also …

It is now widely recognised that extracellular nucleotides, signalling via purinergic receptors,
participate in numerous biological processes in most tissues. It has become evident that …

Although light is essential for photosynthesis, excess light can damage the photosynthetic
apparatus and deregulate other cellular processes. Thus, protective integrated regulatory …

OBJECTIVE—To determine whether middle-aged premenopausal women with type 1
diabetes had more self-reported fractures and lower bone mineral density (BMD) compared …

Regulation of load‐induced bone formation is considered a local phenomenon controlled by
osteocytes, although it has also been hypothesized that functional adaptation may be …

Patients with type 2 diabetes mellitus (T2DM) and/or cardiovascular disease (CVD),
conditions of hyperinsulinaemia, have lower levels of osteocalcin and bone remodelling …

Background Calcitonin gene related peptide (CGRP) is a neuropeptide that is abundant in
the sensory neurons which innervate bone. The effects of CGRP on isolated bone cells have …

Underlying mechanisms contributing to the imbalance in bone turnover during osteoporosis
remain only partially explained. Reduced sensory nerve function may contribute to this …

Although the responses of bone to increased loading or exercise have been studied in
detail, our understanding of the effects of decreased usage of the skeleton has been limited …

Titanium (Ti) biomaterials have been applied to a wide range of implantable medical
devices. When placed in bone marrow, Ti-biomaterials integrate to the surrounding bone …