Natural killer cells in antiviral immunity

NK Björkström, B Strunz, HG Ljunggren - Nature Reviews Immunology, 2022 - nature.com
Natural killer (NK) cells play an important role in innate immune responses to viral infections.
Here, we review recent insights into the role of NK cells in viral infections, with particular …

[HTML][HTML] Innate lymphoid cells: 10 years on

E Vivier, D Artis, M Colonna, A Diefenbach, JP Di Santo… - Cell, 2018 - cell.com
Innate lymphoid cells (ILCs) are lymphocytes that do not express the type of diversified
antigen receptors expressed on T cells and B cells. ILCs are largely tissue-resident cells and …

Single-cell sequencing of human white adipose tissue identifies new cell states in health and obesity

AD Hildreth, F Ma, YY Wong, R Sun, M Pellegrini… - Nature …, 2021 - nature.com
White adipose tissue (WAT) is an essential regulator of energy storage and systemic
metabolic homeostasis. Regulatory networks consisting of immune and structural cells are …

Cells of the human intestinal tract mapped across space and time

R Elmentaite, N Kumasaka, K Roberts, A Fleming… - Nature, 2021 - nature.com
The cellular landscape of the human intestinal tract is dynamic throughout life, developing in
utero and changing in response to functional requirements and environmental exposures …

[HTML][HTML] Single-cell analysis of Crohn's disease lesions identifies a pathogenic cellular module associated with resistance to anti-TNF therapy

JC Martin, C Chang, G Boschetti, R Ungaro, M Giri… - Cell, 2019 - cell.com
Clinical benefits of cytokine blockade in ileal Crohn's disease (iCD) are limited to a subset of
patients. Here, we applied single-cell technologies to iCD lesions to address whether …

[HTML][HTML] Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response

K Golebski, JA Layhadi, U Sahiner, EH Steveling-Klein… - Immunity, 2021 - cell.com
The role of innate immune cells in allergen immunotherapy that confers immune tolerance to
the sensitizing allergen is unclear. Here, we report a role of interleukin-10-producing type 2 …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Tissue-resident immune cells in humans

JI Gray, DL Farber - Annual review of immunology, 2022 - annualreviews.org
Tissue-resident immune cells span both myeloid and lymphoid cell lineages, have been
found in multiple human tissues, and play integral roles at all stages of the immune …

The broad spectrum of human natural killer cell diversity

AG Freud, BL Mundy-Bosse, J Yu, MA Caligiuri - Immunity, 2017 - cell.com
Natural killer (NK) cells provide protection against infectious pathogens and cancer. For
decades it has been appreciated that two major NK cell subsets (CD56 bright and CD56 …

Plasticity of innate lymphoid cell subsets

SM Bal, K Golebski, H Spits - Nature Reviews Immunology, 2020 - nature.com
Innate lymphoid cells (ILCs) are important for tissue homeostasis and for the initiation of
immune responses. Based on their transcriptional regulation and cytokine profiles, ILCs can …