Phyto‐pharmacological perspective of Silymarin: A potential prophylactic or therapeutic agent for COVID‐19, based on its promising immunomodulatory, anti …
P Palit, A Mukhopadhyay… - Phytotherapy …, 2021 - Wiley Online Library
Coronavirus disease 2019 (COVID‐19) triggered by a new viral pathogen, named severe
acute respiratory syndrome Coronavirus‐2 (SARS‐CoV‐2), is now a global health …
acute respiratory syndrome Coronavirus‐2 (SARS‐CoV‐2), is now a global health …
IL-6/IL-6R pathway is a therapeutic target in chemoresistant ovarian cancer
Introduction: Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy
worldwide and despite an initial response to therapeutic agents, the majority of patients …
worldwide and despite an initial response to therapeutic agents, the majority of patients …
Silibinin restores the sensitivity of cisplatin and taxol in A2780-resistant cell and reduces drug-induced hepatotoxicity
Z Yang, Q Pan, D Zhang, J Chen, Y Qiu… - Cancer management …, 2019 - Taylor & Francis
Purpose Ovarian cancer is the most lethal cancer among all gynaecological malignancies.
The combination theraputics of cisplatin and taxol is widely used in clinicals for ovarian …
The combination theraputics of cisplatin and taxol is widely used in clinicals for ovarian …
[HTML][HTML] Silibinin exhibits anti-tumor effects in a breast cancer stem cell model by targeting stemness and induction of differentiation and apoptosis
J Firouzi, F Sotoodehnejadnematalahi… - BioImpacts …, 2022 - ncbi.nlm.nih.gov
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Introduction: Malignant breast cancer (BC) frequently contains a rare population of cells …
Introduction: Malignant breast cancer (BC) frequently contains a rare population of cells …
Acquired expression of osteopontin selectively promotes enrichment of leukemia stem cells through AKT/mTOR/PTEN/β-catenin pathways in AML cells
S Mohammadi, SH Ghaffari, M Shaiegan, MN Zarif… - Life sciences, 2016 - Elsevier
Aims Acute myeloid leukemia (AML) initiation and progression have been attributed to
subpopulations of self-renewing leukemia stem cells (LSCs), which contribute to …
subpopulations of self-renewing leukemia stem cells (LSCs), which contribute to …
Thalidomide attenuates development of morphine dependence in mice by inhibiting PI3K/Akt and nitric oxide signaling pathways
Morphine dependence and the subsequent withdrawal syndrome restrict its clinical use in
management of chronic pain. The precise mechanism for the development of dependence is …
management of chronic pain. The precise mechanism for the development of dependence is …
Thalidomide attenuates the development and expression of antinociceptive tolerance to μ-opioid agonist morphine through l-arginine-iNOS and nitric oxide pathway
Morphine is a μ-opioid analgesic drug which is used in the treatment and management of
chronic pain. However, due to development of antinociceptive tolerance its clinical use is …
chronic pain. However, due to development of antinociceptive tolerance its clinical use is …
Silibinin‐induced endoplasmic reticulum stress and mitochondrial dysfunction suppress growth of endometriotic lesions
Silibinin is a flavonolignan extracted from milk thistle, which has been used for treating liver
disorders, various cancers, and gynecological diseases. However, attempts for treating …
disorders, various cancers, and gynecological diseases. However, attempts for treating …
Evidence for the involvement of nitric oxide in cholestasis-induced itch associated response in mice
Cholestasis is a major systemic disorder associated with distressing pruritus (itch). Nitric
oxide (NO) is a neurotransmitter, assumed to be involved in pruritus. Based on over …
oxide (NO) is a neurotransmitter, assumed to be involved in pruritus. Based on over …
Involvement of nitrergic system in anticonvulsant effect of zolpidem in lithium-pilocarpine induced status epilepticus: evaluation of iNOS and COX-2 genes expression
This study aims to investigate the role of zolpidem in lithium-pilocarpine induced status
epilepticus (SE) and probable mechanisms involved in seizure threshold alteration. In the …
epilepticus (SE) and probable mechanisms involved in seizure threshold alteration. In the …