Application of atomic force microscopy in cancer research

X Deng, F Xiong, X Li, B Xiang, Z Li, X Wu… - Journal of …, 2018 - Springer
Atomic force microscopy (AFM) allows for nanometer-scale investigation of cells and
molecules. Recent advances have enabled its application in cancer research and diagnosis …

Atomic force microscopy as a tool for assessing the cellular elasticity and adhesiveness to identify cancer cells and tissues

J Zemła, J Danilkiewicz, B Orzechowska… - Seminars in cell & …, 2018 - Elsevier
From the first experiments of the atomic force microscopy (AFM) with biological samples, the
range of its potential applications grows extensively. One of them is the use of AFM to …

Substrate stiffness modulates the growth, phenotype, and chemoresistance of ovarian cancer cells

Y Fan, Q Sun, X Li, J Feng, Z Ao, X Li… - Frontiers in cell and …, 2021 - frontiersin.org
Mechanical factors in the tumor microenvironment play an important role in response to a
variety of cellular activities in cancer cells. Here, we utilized polyacrylamide hydrogels with …

Mapping mechanical properties of living cells at nanoscale using intrinsic nanopipette–sample force interactions

VS Kolmogorov, AS Erofeev, E Woodcock, YM Efremov… - Nanoscale, 2021 - pubs.rsc.org
Mechanical properties of living cells determined by cytoskeletal elements play a crucial role
in a wide range of biological functions. However, low-stress mapping of mechanical …

[HTML][HTML] Ultrasound-responsive microbubbles and nanodroplets: A pathway to targeted drug delivery

G Shakya, M Cattaneo, G Guerriero, A Prasanna… - Advanced Drug Delivery …, 2024 - Elsevier
Ultrasound-responsive agents have shown great potential as targeted drug delivery agents,
effectively augmenting cell permeability and facilitating drug absorption. This review focuses …

Advanced technological tools to study multidrug resistance in cancer

L Andrei, S Kasas, IO Garrido, T Stanković… - Drug Resistance …, 2020 - Elsevier
The complexity of cancer biology and its clinical manifestation are driven by genetic,
epigenetic, transcriptomic, proteomic and metabolomic alterations, supported by genomic …

[HTML][HTML] Recent advances in determining the cellular-level property evolutions of plant-based food materials during drying

VTW Thuppahige, ZG Welsh, M Joardder… - Trends in Food Science & …, 2024 - Elsevier
Background Determination of the changes in cellular-level structural, mechanical,
rheological and transport properties during the processing of plant-based food materials …

Applicability of atomic force microscopy to determine cancer-related changes in cells

M Lekka - … Transactions of the Royal Society A, 2022 - royalsocietypublishing.org
The determination of mechanical properties of living cells as an indicator of cancer
progression has become possible with the development of local measurement techniques …

Nanomechanics in monitoring the effectiveness of drugs targeting the cancer cell cytoskeleton

A Kubiak, T Zieliński, J Pabijan, M Lekka - International Journal of …, 2020 - mdpi.com
Increasing attention is devoted to the use of nanomechanics as a marker of various
pathologies. Atomic force microscopy (AFM) is one of the techniques that could be applied to …

Atomic Force Microscopy Methods to Measure Tumor Mechanical Properties

J Najera, MR Rosenberger, M Datta - Cancers, 2023 - mdpi.com
Simple Summary Atomic force microscopy (AFM) is a powerful technique that has been
pivotal to cancer research, but it has only recently been used to study tumor pathology at the …