Inflammatory bowel disease (IBD) is a chronic, recurrent inflammatory disease of the
gastrointestinal tract. In addition to digestive symptoms, patients with IBD may also develop …

There is an increasing interest in the pathophysiological role of the kynurenine pathway of
tryptophan metabolism in the regulation of immune function and inflammation. We sought to …

Background Osteoarthritis (OA) is one of the most prevalent musculoskeletal diseases and is
the leading cause of pain and disability in the aged population. However, the underlying …

Spondyloarthritis (SpA) is a group of rheumatic diseases that cause joint inflammation.
Accumulating studies have focused on the metabolomic profiling of SpA in recent years. We …

Endometritis is a serious reproductive disease in mammals that commonly results in
reproductive loss and even permanent infertility. Kynurenic acid (KYNA) is the main …

The gut microbiota plays a pivotal role in regulating host immunity, and dysregulation of this
interaction is implicated in autoimmune and inflammatory diseases, including …

ABSTRACT Background Familial Mediterranean fever (FMF) is an autoinflammatory
syndrome characterized by recurrent episodes of fever and aseptic polyserositis. Subclinical …

Objective We aimed to investigate the plasma levels of tryptophan (Trp) and its metabolites
in patients with primary Sjögren's syndrome (pSS). Methods The study included 34 pSS …

Objectives Spondyloarthritis (SpA) is a group of immune‐mediated diseases highly
concomitant with non‐musculoskeletal inflammatory disorders, such as acute anterior uveitis …

Objective Ankylosing spondylitis (AS) exhibits paradoxical bone features typically
characterized by new bone formation and systemic bone loss. Although abnormal …