Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection

SH Safiabadi Tali, JJ LeBlanc, Z Sadiq… - Clinical microbiology …, 2021 - Am Soc Microbiol
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …

Testing at scale during the COVID-19 pandemic

TR Mercer, M Salit - Nature Reviews Genetics, 2021 - nature.com
Assembly and publication of the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) genome in January 2020 enabled the immediate development of tests to detect the …

Quantitative SARS-CoV-2 viral-load curves in paired saliva samples and nasal swabs inform appropriate respiratory sampling site and analytical test sensitivity …

ES Savela, A Viloria Winnett, AE Romano… - Journal of clinical …, 2022 - Am Soc Microbiol
Early detection of SARS-CoV-2 infection is critical to reduce asymptomatic and
presymptomatic transmission, curb the spread of variants, and maximize treatment efficacy …

Molecular diagnostic assays for COVID-19: an overview

P Habibzadeh, M Mofatteh, M Silawi… - Critical reviews in …, 2021 - Taylor & Francis
Abstract The coronavirus disease 2019 (COVID-19) pandemic has highlighted the cardinal
importance of rapid and accurate diagnostic assays. Since the early days of the outbreak …

COVID-19 surveillance in wastewater: An epidemiological tool for the monitoring of SARS-CoV-2

S Maryam, I Ul Haq, G Yahya, M Ul Haq… - Frontiers in cellular …, 2023 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic has prompted a lot of questions
globally regarding the range of information about the virus's possible routes of transmission …

[HTML][HTML] Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2–induced systemic toxicity

S Li, F Ma, T Yokota, G Garcia Jr, A Palermo, Y Wang… - JCI insight, 2021 - ncbi.nlm.nih.gov
Extrapulmonary manifestations of COVID-19 are associated with a much higher mortality
rate than pulmonary manifestations. However, little is known about the pathogenesis of …

Multiplexed detection of SARS-CoV-2 and other respiratory infections in high throughput by SARSeq

R Yelagandula, A Bykov, A Vogt, R Heinen… - Nature …, 2021 - nature.com
The COVID-19 pandemic has demonstrated the need for massively-parallel, cost-effective
tests monitoring viral spread. Here we present SARSeq, saliva analysis by RNA sequencing …

LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding

KU Ludwig, RM Schmithausen, D Li, ML Jacobs… - Nature …, 2021 - nature.com
Frequent testing of large population groups combined with contact tracing and isolation
measures will be crucial for containing Coronavirus Disease 2019 outbreaks. Here we …

A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2

MM Aynaud, JJ Hernandez, S Barutcu… - Nature …, 2021 - nature.com
Population scale sweeps of viral pathogens, such as SARS-CoV-2, require high intensity
testing for effective management. Here, we describe “Systematic Parallel Analysis of RNA …

Assessment of a smartphone-based loop-mediated isothermal amplification assay for detection of SARS-CoV-2 and influenza viruses

DM Heithoff, L Barnes, SP Mahan, GN Fox… - JAMA network …, 2022 - jamanetwork.com
Importance A critical need exists in low-income and middle-income countries for low-cost,
low-tech, yet highly reliable and scalable testing for SARS-CoV-2 virus that is robust against …