Nowadays, drug resistance in parasites is considered to be one of the foremost concerns in
health and disease management. It is interconnected worldwide and undermines the health …

Most rapid diagnostic tests for Plasmodium falciparum malaria target the Histidine-Rich
Proteins 2 and 3 (HRP2 and HRP3). Deletions of the hrp2 and hrp3 genes result in false …

Malaria remains a leading cause of death and disease in many tropical and subtropical
regions of the world. Due to the alarming spread of resistance to almost all available …

Malaria results in over 600,000 deaths annually, with the highest burden of deaths in young
children living in sub-Saharan Africa. Molecular surveillance can provide important …

Polymorphisms in the Plasmodium falciparum multidrug resistance protein 1 (pfmdr1) gene
and the Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene alter the …

Amino acid substitutions within the conserved polypeptide sequence of the insect olfactory
receptor co-receptor (Orco) have been demonstrated to influence its pharmacological …

Genomic epidemiology holds promise for malaria control and elimination efforts, for example
by informing on Plasmodium falciparum genetic diversity and prevalence of mutations …

Malaria is a global public health priority causing over 600,000 deaths annually, mostly
young children living in Sub-Saharan Africa. Molecular surveillance can provide key …

Plasmodium falciparum multidrug resistance constitutes a major obstacle to the global
malaria elimination campaign. Specific mutations in the Plasmodium falciparum chloroquine …

Background Molecular and genomic surveillance is becoming increasingly used to track
malaria control and elimination efforts. Blood samples can be collected as whole blood and …