Brain-derived neurotrophic factor (BDNF) is a neuropeptide that plays numerous important
roles in synaptic development and plasticity. While its importance in fundamental physiology …

Neurotrophic factors, particularly BDNF (brain-derived neurotrophic factor), have been
associated with depression and antidepressant drug action. A variety of preclinical and …

Major depressive disorder is a debilitating disorder affecting millions of people each year.
Brain-derived neurotrophic factor (BDNF) and inflammation are two prominent biologic risk …

Depression is a well-known disabling mental illness characterized by sadness, loss of
interest in activities, and decreased energy. The symptoms of depression are usually …

The neuroimmune system plays a crucial role in the regulation of mood disorders. Moreover,
recent studies show that brain-derived neurotrophic factor (BDNF), a member of the …

Major depressive disorder (MDD) patients display a common but often variable set of
symptoms making successful, sustained treatment difficult to achieve. Separate depressive …

Ketamine produces rapid antidepressant action in patients with major depression or
treatment-resistant depression. Studies have identified brain-derived neurotrophic factor …

The neurotrophin brain-derived neurotrophic factor (BDNF) stimulates adult neurogenesis,
but also influences structural plasticity and function of serotonergic neurons. Both …

ABSTRACT Introduction: Serotonin (5-HT) and brain-derived neurotrophic factor (BDNF) are
known as principal players in different kinds of plasticity. The 5-HT–BDNF interaction in early …

Brain-derived neurotrophic factor (BDNF) and its high-affinity receptor, tropomyosin receptor
kinase B (TrkB), regulate long-term potentiation (LTP) in the hippocampus, although the …