Lewis base–boryl radicals enabled borylation reactions and selective activation of carbon–heteroatom bonds

TY Peng, FL Zhang, YF Wang - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus The past decades have witnessed tremendous progress on radical reactions.
However, in comparison with carbon, nitrogen, oxygen, and other main group element …

Visible-Light-Induced Cascade Cyclization of 3-(2-(Ethynyl)phenyl)quinazolinones to Phosphorylated Quinolino[2,1-b]quinazolinones

FL Zeng, ZY Zhang, PC Yin, FK Cheng, XL Chen… - Organic …, 2022 - ACS Publications
3-(2-(Ethynyl) phenyl) quinazolinones were designed and synthesized as a class of novel
and efficient skeletons for phosphorylation/cyclization reactions. Under visible light …

[HTML][HTML] Ynones in dearomative spirocyclisation processes; a review

RJK Taylor, WP Unsworth - Tetrahedron Chem, 2024 - Elsevier
This review concentrates on our research into the discovery of novel ynone-based
dearomative spirocyclisation processes, whilst placing the new chemistry into the context of …

Photoredox-Catalyzed Strain-Release-Driven Synthesis of Functionalized Spirocyclobutyl Oxindoles

T Singha, NA Bapat, SK Mishra, DP Hari - Organic Letters, 2024 - ACS Publications
Spirocyclobutyl oxindoles have garnered substantial attention in drug discovery and
pharmaceuticals owing to their wide range of biological activities. Strain-release in small …

Cp2Fe Mediated Electrochemical Synthesis of Phosphonylated Spirocyclic Indolines via Dearomatization of Indoles

K Mo, X Zhou, J Wang, J Wu, Y Zhao - Organic Letters, 2023 - ACS Publications
A general and robust strategy for the synthesis of phosphonylated spirocyclic indolines has
been developed through Cp2Fe-catalyzed electrochemical dearomaztizaion of indoles …

Iron‐Catalyzed Silylation and Spirocyclization of Biaryl‐Ynones: A Radical Cascade Process toward Silylated Spiro [5.5] trienones

F Chen, Y Zheng, H Yang, QY Yang… - … Synthesis & Catalysis, 2022 - Wiley Online Library
Iron‐catalyzed cascade silyl radical addition/6‐exo‐trig cyclization/dearomatization of biaryl
ynones has been developed. This approach uses silane as the precursor of silyl radical as …

Electrosynthesis of spiro-indolenines via dearomative arylation of indoles in batch and continuous flow

W Zhao, Y Lu, Y Qiao, X Yin, C Liu, Z Fang, J Zhu… - Organic …, 2023 - ACS Publications
An electrosynthesis of spiro-indolenines in batch and continuous flow was achieved through
dearomative arylation of indoles with good functional group compatibility. User-friendly …

Ag (i)-catalyzed dearomatizing spirocyclization/nucleophile addition cascade reactions of indole-tethered ynones

D Bag, SD Sawant - Chemical Communications, 2023 - pubs.rsc.org
Ag (I)-catalyzed highly diastereoselective construction of divergent spiroindolines is
disclosed herein. The approach proceeds via dearomatizing spirocyclization of indole …

Access to Diverse Seleno-spirocyclohexadienones via Ag(II)-Catalyzed Selenylative ipso-Annulation with Se and Boronic Acids

C Raji Reddy, M Subbarao, DH Kolgave… - ACS …, 2022 - ACS Publications
An efficient and straightforward synthesis of diversified seleno-azaspiro-2, 5-
cyclohexadienones from N-(4-methoxy aryl) propiolamides using elemental selenium and …

Copper catalyzed dearomatization by Michael-type addition of indolyl ynones: divergent synthesis of functionalized spiroindoles and cyclopenta [c] quinolin-3-ones

GX Ru, M Zhang, TT Zhang, XL Jiang… - Organic Chemistry …, 2022 - pubs.rsc.org
Described herein is a novel copper-catalyzed multifunctionalization of alkyne-tethered
indoles, allowing the practical and efficient synthesis of a diverse array of valuable …