Novel microneedle platforms for the treatment of wounds by drug delivery: a review

H An, Z Gu, Z Huang, T Huo, Y Xu, Y Dong… - Colloids and Surfaces B …, 2024 - Elsevier
The management and treatment of wounds are complex and pose a substantial financial
burden to the patient. However, the complex environment of wounds leads to inadequate …

Exploring the synthesis, properties, and potential of chitosan-functionalized metal-organic frameworks in emerging applications

A Sathiyaseelan, X Zhang, Y Lu, NA l Azeez… - Progress in Materials …, 2024 - Elsevier
Chitosan (CS), a natural cationic biopolymer, has emerged as a promising component for
synthesizing biological/bioinspired metal–organic frameworks (BioMOFs). CS's abundant …

Composite microneedles loaded with Astragalus membranaceus polysaccharide nanoparticles promote wound healing by curbing the ROS/NF-κB pathway to …

X Liu, C Guo, W Yang, W Wang, N Diao, M Cao… - Carbohydrate …, 2024 - Elsevier
The healing of chronic diabetic wounds remains a formidable challenge in modern times. In
this study, a novel traditional Chinese medicine microneedle patch was designed based on …

Applications and prospects of new transdermal drug delivery system based on metal-organic frameworks for diabetic wound healing

Q Huang, Y Zeng, Y Qiu, J Zou, F Li, X Liu… - Dyes and …, 2024 - Elsevier
Due to the particular physiological environment of high blood sugar in diabetic patients, the
wound healing of diabetic patients is much more complicated than that of normal wounds …

Research Progress of Hydrogel Microneedles in Wound Management

M Ji, F Zhan, X Qiu, H Liu, X Liu, P Bu… - ACS Biomaterials …, 2024 - ACS Publications
Microneedles are a novel drug delivery system that offers advantages such as safety,
painlessness, minimally invasive administration, simplicity of use, and controllable drug …

Nanocomposite Hydrogel for Real‐Time Wound Status Monitoring and Comprehensive Treatment

H Lei, X Yu, D Fan - Advanced Science, 2024 - Wiley Online Library
Current skin sensors or wound dressings fall short in addressing the complexities and
challenges encountered in real‐world scenarios, lacking adequate capability to facilitate …

Antisense yycF and BMP-2 co-delivery gelatin methacryloyl and carboxymethyl chitosan hydrogel composite for infective bone defects regeneration

B Qin, H Dong, X Tang, Y Liu, G Feng, S Wu… - International Journal of …, 2023 - Elsevier
Repairing infected bone defects remains a challenge in clinical work. Intractable bacterial
infections and insufficient osseointegration are major concerns for infected bone defects. To …

The Progress in the Application of Dissolving Microneedles in Biomedicine

X Yu, J Zhao, D Fan - Polymers, 2023 - mdpi.com
In recent years, microneedle technology has been widely used for the transdermal delivery
of substances, showing improvements in drug delivery effects with the advantages of …

Recent Advances in Biomacromolecule‐Reinforced 2D Material (2DM) Hydrogels: From Interactions, Synthesis, and Functionalization to Biomedical Applications

G Gu, Z Cui, X Du, P He, C Rong, H Tao… - Advanced Functional …, 2024 - Wiley Online Library
Regenerative biomedicine has emerged as a forefront area in medical research, heralding a
new era of therapeutic strategies. This review delineates the integration of 2D materials …

Nanofibrous dressing with drug/electroactivity synergistic effect for wound healing

J Chen, X Jia, S Wang, X Wang, L Li, G Han… - Chemical Engineering …, 2024 - Elsevier
Although electrical stimulation (ES) and drugs are desirable for wound healing, dressings
that combine ES and drugs are scarce. In this study, an electroactive drug-loaded …