How widespread is adult neurogenesis in mammals?

E Gould - Nature Reviews Neuroscience, 2007 - nature.com
It is now widely accepted that neurogenesis occurs in two regions of the adult mammalian
brain—the hippocampus and the olfactory bulb. There is evidence for adult neurogenesis in …

Functions of microglia in the central nervous system–beyond the immune response

H Wake, AJ Moorhouse, J Nabekura - Neuron glia biology, 2011 - cambridge.org
Microglia cells are the immune cells of the central nervous system and consequently play
important roles in brain infections and inflammation. Recent in vivo imaging studies have …

Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primates

TD Perera, JD Coplan, SH Lisanby… - Journal of …, 2007 - Soc Neuroscience
New neurons are generated in the adult hippocampus of many species including rodents,
monkeys, and humans. Conditions associated with major depression, such as social stress …

Maturation time of new granule cells in the dentate gyrus of adult macaque monkeys exceeds six months

SJ Kohler, NI Williams, GB Stanton… - Proceedings of the …, 2011 - National Acad Sciences
We studied two groups of adult macaque monkeys to determine the time course of adult
neurogenesis in the dentate gyrus of the hippocampus. In the first group, six adult monkeys …

Repairing brain after stroke: a review on post-ischemic neurogenesis

C Wiltrout, B Lang, Y Yan, RJ Dempsey… - Neurochemistry …, 2007 - Elsevier
Stroke is devastating as currently no therapies are available that can prevent stroke-induced
neurological dysfunction in humans. With the recent observations that acute insults to adult …

Noninvasive strategies to promote functional recovery after stroke

A Faralli, M Bigoni, A Mauro, F Rossi… - Neural plasticity, 2013 - Wiley Online Library
Stroke is a common and disabling global health‐care problem, which is the third most
common cause of death and one of the main causes of acquired adult disability in many …

Interruption of β-catenin signaling reduces neurogenesis in Alzheimer's disease

P He, Y Shen - Journal of Neuroscience, 2009 - Soc Neuroscience
The neuronal loss associated with Alzheimer's disease (AD) affects areas of the brain that
are vital to cognition. Although recent studies have shown that new neurons can be …

Adult human neurogenesis: from microscopy to magnetic resonance imaging

A Sierra, JM Encinas, M Maletic-Savatic - Frontiers in neuroscience, 2011 - frontiersin.org
Neural stem cells reside in well-defined areas of the adult human brain and are capable of
generating new neurons throughout the life span. In rodents, it is well established that the …

Neurogenesis in primates versus rodents and the value of non-human primate models

R Zhang, H Quan, Y Wang, F Luo - National Science Review, 2023 - academic.oup.com
Neurogenesis, the process of generating neurons from neural stem cells, occurs during both
embryonic and adult stages, with each stage possessing distinct characteristics. Dysfunction …

Understanding the real state of human adult hippocampal neurogenesis from studies of rodents and non-human primates

T Seki - Frontiers in Neuroscience, 2020 - frontiersin.org
The concept of adult hippocampal neurogenesis (AHN) has been widely accepted, and a
large number of studies have been performed in rodents using modern experimental …