Many endemic poverty-associated diseases, such as malaria and leishmaniasis, are
transmitted by arthropod vectors. Pathogens must interact with specific molecules in the …

The use of glycosylphosphatidylinositol (GPI) to anchor proteins to the cell surface is
widespread among eukaryotes. The GPI-anchor is covalently attached to the C-terminus of a …

The complex gut microbiome is a malleable microbial community that can undergo
remodeling in response to many factors, including the gut environment and microbial …

The long and complex Trypanosoma brucei development in the tsetse fly vector culminates
when parasites gain mammalian infectivity in the salivary glands. A key step in this process …

Signaling from ciliary microdomains controls developmental processes in metazoans.
Trypanosome transmission requires development and migration in the tsetse vector …

Endocytosis is a common process observed in most eukaryotic cells, although its complexity
varies among different organisms. In Trypanosoma brucei, the endocytic machinery is under …

To best understand parasite, host, and vector morphologies, host–parasite interactions, and
to develop new drug and vaccine targets, structural data should, ideally, be obtained and …

The collective movement of African trypanosomes on semi-solid surfaces, known as social
motility, is presumed to be due to migration factors and repellents released by the parasites …

Mitochondrial metabolic remodeling is a hallmark of the Trypanosoma brucei digenetic life
cycle because the insect stage utilizes a cost-effective oxidative phosphorylation (OxPhos) …

Using serial block-face scanning electron microscopy, we report on the internal 3D
structures of the brown planthopper, Nilaparvata lugens (Hemiptera: Delphacidae) at …