[HTML][HTML] FASconCAT-G: extensive functions for multiple sequence alignment preparations concerning phylogenetic studies
Background Phylogenetic and population genetic studies often deal with multiple sequence
alignments that require manipulation or processing steps such as sequence concatenation …
alignments that require manipulation or processing steps such as sequence concatenation …
Prevalence of transfusion-transmitted infections in multiple blood transfusion-dependent thalassemic patients in Asia: A systemic review
Background Thalassemia is a hereditary hemolytic anemia marked by a defect in
synthesizing one or more globin chains in hemoglobin. In Pakistan, approximately 10,000 …
synthesizing one or more globin chains in hemoglobin. In Pakistan, approximately 10,000 …
Thalassemia: impact of consanguineous marriages on most prevalent monogenic disorders of humans
U Saeed, ZZ Piracha - Asian Pacific Journal of Tropical Disease, 2016 - Elsevier
Thalassaemia is an inherited autosomal recessive disorder closely associated with
consanguineous marriages. A literature search was conducted with an aim to investigate …
consanguineous marriages. A literature search was conducted with an aim to investigate …
Identification of a pegivirus (GB virus-like virus) that infects horses
A Kapoor, P Simmonds, JM Cullen, TKH Scheel… - Journal of …, 2013 - Am Soc Microbiol
The recent identification of nonprimate hepaciviruses in dogs and then in horses prompted
us to look for pegiviruses (GB virus-like viruses) in these species. Although none were …
us to look for pegiviruses (GB virus-like viruses) in these species. Although none were …
Hepatitis C virus genetic variability and the presence of NS5B resistance-associated mutations as natural polymorphisms in selected genotypes could affect the …
Because of the extreme genetic variability of hepatitis C virus (HCV), we analyzed the NS5B
polymerase genetic variability in circulating HCV genotypes/subtypes and its impact on the …
polymerase genetic variability in circulating HCV genotypes/subtypes and its impact on the …
Sensitive detection of hepatitis C virus using a catalytic hairpin assembly coupled with a lateral flow immunoassay test strip
F Su, M Zou, H Wu, F Xiao, Y Sun, C Zhang, W Gao… - Talanta, 2022 - Elsevier
Currently, PCR is the gold standard for the detection of hepatitis C virus (HCV). However, the
PCR technique is complicated and time-consuming, which prevents its application and …
PCR technique is complicated and time-consuming, which prevents its application and …
Estimation of hepatitis B virus, hepatitis C virus, and different clinical parameters in the thalassemic population of capital twin cities of Pakistan
Hepatitis B and C are serious public health problems worldwide. Thalassemia patients are
dependent on blood transfusions throughout their life and are at high risk of viral infections …
dependent on blood transfusions throughout their life and are at high risk of viral infections …
[HTML][HTML] Amino acid substitutions in genotype 3a hepatitis C virus polymerase protein affect responses to sofosbuvir
Background & Aims Sofosbuvir is a frequently used pan-genotype inhibitor of hepatitis C
virus (HCV) polymerase. This drug eliminates most chronic HCV infections, and resistance …
virus (HCV) polymerase. This drug eliminates most chronic HCV infections, and resistance …
[HTML][HTML] Identifying different mutation sites leading to resistance to the direct-acting antiviral (DAA) sofosbuvir in hepatitis C virus patients from Egypt
The hepatitis C virus (HCV) is a major global health challenge and a leading cause of
morbidity and mortality. Many direct-acting antivirals (DAAs) target essential …
morbidity and mortality. Many direct-acting antivirals (DAAs) target essential …
Induction of genotype cross-reactive, hepatitis C virus-specific, cell-mediated immunity in DNA-vaccinated mice
DK Wijesundara, J Gummow, Y Li, W Yu… - Journal of …, 2018 - Am Soc Microbiol
ABSTRACT A universal hepatitis C virus (HCV) vaccine should elicit multiantigenic,
multigenotypic responses, which are more likely to protect against challenge with the range …
multigenotypic responses, which are more likely to protect against challenge with the range …