Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …

Colorectal cancer (CRC) is a heterogeneous disease of the intestinal epithelium that is
characterized by the accumulation of mutations and a dysregulated immune response. Up to …

Macroautophagy/autophagy is a cellular catabolic process that results in lysosome-
mediated recycling of organelles and protein aggregates, as well as the destruction of …

Colorectal cancer (CRC) is the third most common and the second most fatal cancer. In
recent years, more attention has been directed toward the role of gut microbiota in the …

Various bacteria are suggested to contribute to colorectal cancer (CRC) development,,,–,
including pks+ Escherichia coli, which produces the genotoxin colibactin that induces …

Colorectal cancer (CRC) is a leading cause of cancer morbidity and mortality worldwide.
The etiology and pathogenesis of CRC remain unclear. A growing body of evidence …

Bisphenol A (BPA) is a common environmental contaminant, whose exposure is associated
with the progression of various kidney diseases. BPA exposure has turned out to be …

Fructose is associated with colorectal cancer tumorigenesis and metastasis through
ketohexokinase-mediated metabolism in the colorectal epithelium, yet its role in the tumor …

Colibactin is a secondary metabolite encoded by the pks gene island identified in several
Enterobacteriaceae, including some pathogenic Escherichia coli (E. coli) commonly …

Colitis-associated colon cancer (CAC) is a distinct form of colorectal cancer that emerges
from prolonged colitis in individuals with inflammatory bowel disease (IBD). Chronic …