The dynamic nuclear envelope: Resilience in health and dysfunction in disease
AM Turkmen, NO Saik, KS Ullman - Current Opinion in Cell Biology, 2023 - Elsevier
The canonical appearance of the nucleus depends on constant adaptation and remodeling
of the nuclear envelope in response to changing biomechanical forces and metabolic …
of the nuclear envelope in response to changing biomechanical forces and metabolic …
[HTML][HTML] Tau beyond Tangles: DNA Damage Response and Cytoskeletal Protein Crosstalk on Neurodegeneration
M Asada-Utsugi, M Urushitani - International Journal of Molecular …, 2024 - mdpi.com
Neurons in the brain are continuously exposed to various sources of DNA damage.
Although the mechanisms of DNA damage repair in mitotic cells have been extensively …
Although the mechanisms of DNA damage repair in mitotic cells have been extensively …
Loss of EIF4G2 mediates aggressiveness in distinct human endometrial cancer subpopulations with poor survival outcome in patients
S Meril, M Muhlbauer Avni, C Lior, M Bahlsen… - Oncogene, 2024 - nature.com
The non-canonical translation initiation factor EIF4G2 plays essential roles in cellular stress
responses via translation of selective mRNA cohorts. Currently there is limited and …
responses via translation of selective mRNA cohorts. Currently there is limited and …
Circadian PERIOD proteins regulate TC-DSB repair through anchoring to the nuclear envelope
B Le Bozec, L Guitton-Sert, S Collins, AL Finoux… - bioRxiv, 2023 - biorxiv.org
Abstract Repair of DNA Double-Strand Breaks (DSBs) produced in transcriptionally active
chromatin occurs through a poorly characterized pathway called Transcription-Coupled DSB …
chromatin occurs through a poorly characterized pathway called Transcription-Coupled DSB …
Behind the stoNE wall: a fervent activity for nuclear lipids
K Samardak, J Bâcle, M Moriel-Carretero - Biochimie, 2024 - Elsevier
The four main types of biomolecules are nucleic acids, proteins, carbohydrates and lipids.
The knowledge about their respective interactions is as important as the individual …
The knowledge about their respective interactions is as important as the individual …
[HTML][HTML] Protocol for machine-learning-based 3D image analysis of nuclear envelope tubules in cultured cells
A Hundal, D Urman, M Stanic, R Hakem, K Mekhail - STAR protocols, 2024 - Elsevier
The nuclear envelope can form complex structures in physiological and pathological
contexts. Current approaches to quantify nuclear envelope structures can be time …
contexts. Current approaches to quantify nuclear envelope structures can be time …
The DNA Replication Checkpoint Targets the Kinetochore for Relocation of Collapsed Forks to the Nuclear Periphery
T Maclay, J Whalen, M Johnson, CH Freudenreich - bioRxiv, 2024 - biorxiv.org
Hairpin forming expanded CAG/CTG repeats pose significant challenges to DNA replication
which can lead to replication fork collapse. Long CAG/CTG repeat tracts relocate to the …
which can lead to replication fork collapse. Long CAG/CTG repeat tracts relocate to the …
[PDF][PDF] Replication forks associated with long nuclear actin filaments in mild stress conditions display increased dynamics.
C Merigliano, MD Palumbieri, M Lopes… - Micropublication …, 2024 - micropublication.org
Nuclear actin filaments (F-actin) form during S-phase and in response to replication stress to
promote fork remodeling and repair. In mild replication stress conditions, nuclear actin …
promote fork remodeling and repair. In mild replication stress conditions, nuclear actin …
Nucleoporins cooperate with Polycomb silencers to promote transcriptional repression and repair at DNA double strand breaks
Y Kee, H Song, Y Bae, S Kim, D Deascanis, Y Lee… - 2024 - researchsquare.com
DNA Double-strand breaks (DSBs) are harmful lesions and major sources of genomic
instability. Studies have suggested that DSBs induce local transcriptional silencing that …
instability. Studies have suggested that DSBs induce local transcriptional silencing that …