Cohort profile update: Tehran cardiometabolic genetic study

MS Daneshpour, M Akbarzadeh, H Lanjanian… - European Journal of …, 2023 - Springer
The Tehran cardiometabolic genetic study (TCGS) is a large population-based cohort study
that conducts periodic follow-ups. TCGS has created a comprehensive database comprising …

Accurate genomic selection using low-density SNP panels preselected by maximum likelihood estimation

S Qu, S Lu, Y Liu, M Li, S Chen - Aquaculture, 2024 - Elsevier
Genomic selection (GS) poses a challenge for the prediction of the genomic estimated
breeding value (GEBV) using a low-density SNP panel. Several methods have been …

The AGT epistasis pattern proposed a novel role for ZBED9 in regulating blood pressure: Tehran Cardiometabolic genetic study (TCGS)

M Akbarzadeh, P Riahi, G Kolifarhood, H Lanjanian… - Gene, 2022 - Elsevier
Introduction High blood pressure is widely regarded as the most important risk factor for
cardiovascular diseases. Epistasis analysis may provide additional insight into the genetic …

The Tehran longitudinal family-based cardiometabolic cohort study sheds new light on dyslipidemia transmission patterns

M Akbarzadeh, P Riahi, AH Saeidian, M Zarkesh… - Scientific Reports, 2024 - nature.com
Dyslipidemia, as a metabolic risk factor, with the strongest and most heritable independent
cause of cardiovascular diseases worldwide. We investigated the familial transmission …

Improvement of genomic predictions in small breeds by construction of genomic relationship matrix through variable selection

E Mancin, LFM Mota, B Tuliozi, R Verdiglione… - Frontiers in …, 2022 - frontiersin.org
Genomic selection has been increasingly implemented in the animal breeding industry, and
it is becoming a routine method in many livestock breeding contexts. However, its use is still …

The effect of family structure on the still-missing heritability and genomic prediction accuracy of type 2 diabetes

M Amiri Roudbar, SM Vahedi, J Jin, M Jahangiri… - Human genomics, 2024 - Springer
This study aims to assess the effect of familial structures on the still-missing heritability
estimate and prediction accuracy of Type 2 Diabetes (T2D) using pedigree estimated risk …

Genome-wide association study on blood pressure traits in the Iranian population suggests ZBED9 as a new locus for hypertension

G Kolifarhood, S Sabour, M Akbarzadeh… - Scientific Reports, 2021 - nature.com
High blood pressure is the heritable risk factor for cardiovascular and kidney diseases.
Genome-wide association studies (GWAS) on blood pressure traits increase our …

Association of dyslipidemia with single nucleotide polymorphisms of the cholesteryl ester transfer protein gene and cardiovascular disease risk factors in a highly …

JMRS Leite, JL Pereira, NRT Damasceno… - Clinical Nutrition …, 2023 - Elsevier
Background and aims Cardiovascular diseases (CVD) are major causes of mortality
worldwide, leading to premature deaths, loss of quality of life, and extensive socioeconomic …

Preselecting Variants from Large-Scale Genome-Wide Association Study Meta-Analyses Increases the Genomic Prediction Accuracy of Growth and Carcass Traits in …

C Wei, C Chang, W Zhang, D Ren, X Cai, T Zhou, S Shi… - Animals, 2023 - mdpi.com
Simple Summary Preselected potential causal variants from genome-wide association
studies (GWASs) for genomic prediction is an appealing strategy for improving the accuracy …

Hypertension risk prediction based on SNPS by machine learning models

SA Lajevardi, M Kargari, MS Daneshpour… - Current …, 2023 - ingentaconnect.com
Background: Hypertension is one of the most significant underlying ailments of
cardiovascular disease; hence, methods that can accurately reveal the risk of hypertension …