A general method to optimize and functionalize red-shifted rhodamine dyes

JB Grimm, AN Tkachuk, L Xie, H Choi, B Mohar… - Nature …, 2020 - nature.com
Expanding the palette of fluorescent dyes is vital to push the frontier of biological imaging.
Although rhodamine dyes remain the premier type of small-molecule fluorophore owing to …

Far-red to NIR emitting xanthene-based fluorophores

Z Khan, N Sekar - Dyes and Pigments, 2023 - Elsevier
Xanthene dyes are well known for their remarkable photophysical property, photostability,
and ability to switch fluorescence on-off depending upon the external environment. Such …

Reductive side of water splitting in artificial photosynthesis: new homogeneous photosystems of great activity and mechanistic insight

TM McCormick, BD Calitree, A Orchard… - Journal of the …, 2010 - ACS Publications
Rhodamine photosensitizers (PSs) substituting S or Se for O in the xanthene ring give
turnover numbers (TONs) as high as 9000 for the generation of hydrogen via the reduction …

Closthioamide: An Unprecedented Polythioamide Antibiotic from the Strictly Anaerobic Bacterium Clostridium cellulolyticum

T Lincke, S Behnken, K Ishida, M Roth… - Angewandte …, 2010 - Wiley Online Library
Bacteria belonging to the genus Clostridium are among the most prominent microorganisms
that lead an obligate anaerobic lifestyle. Clostridia occur in gastrointestinal tracts and are …

Disruption of small molecule transporter systems by Transporter‐Interfering Chemicals (TICs)

SCT Nicklisch, A Hamdoun - FEBS letters, 2020 - Wiley Online Library
Small molecule transporters (SMTs) in the ABC and SLC families are important players in
disposition of diverse endo‐and xenobiotics. Interactions of environmental chemicals with …

Molecular docking characterizes substrate-binding sites and efflux modulation mechanisms within P-glycoprotein.

RJ Ferreira, MJU Ferreira… - Journal of chemical …, 2013 - ACS Publications
P-Glycoprotein (Pgp) is one of the best characterized ABC transporters, often involved in the
multidrug-resistance phenotype overexpressed by several cancer cell lines. Experimental …

Identification of residues in the drug translocation pathway of the human multidrug resistance P-glycoprotein by arginine mutagenesis

TW Loo, MC Bartlett, DM Clarke - Journal of Biological Chemistry, 2009 - ASBMB
P-glycoprotein (P-gp, ATP-binding cassette B1) is a drug pump that extracts toxic drug
substrates from the plasma membrane and catalyzes their ATP-dependent efflux. To map …

Thioxanthylium Cations: Highly Reversible Hydrochromic Mate‐rials with Tunable Color and Moisture Sensitivity

MH Chua, XYD Soo, WP Goh, ZM Png… - … –A European Journal, 2022 - Wiley Online Library
Hydrochromic materials, which change color in response to moisture, are highly sought‐
after due to some unique applications such as moisture detection, humidity monitoring, anti …

Advances in blood–brain barrier modeling in microphysiological systems highlight critical differences in opioid transport due to cortisol exposure

JA Brown, SL Faley, Y Shi, KM Hillgren… - Fluids and Barriers of …, 2020 - Springer
Abstract Background The United States faces a national crisis involving opioid medications,
where currently more than 130 people die every day. To combat this epidemic, a better …

Biomimetic design of protein nanomaterials for hydrophobic molecular transport

D Ren, M Dalmau, A Randall… - Advanced functional …, 2012 - Wiley Online Library
Biomaterials such as self‐assembling biological complexes have a variety of applications in
materials science and nanotechnology. The functionality of protein‐based materials …