Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disease that encompasses a
spectrum of pathological conditions, ranging from simple steatosis (NAFL), nonalcoholic …

Cancer is a key health issue across the world, causing substantial patient morbidity and
mortality. Patient prognosis is tightly linked with metastatic dissemination of the disease to …

Recent advances in tumor biology have revealed that a detailed analysis of the complex
interactions of tumor cells with their adjacent microenvironment (tumor stroma) is mandatory …

Intestinal microbiota determine severity of myocardial infarction in rats. We determined
whether low molecular weight metabolites derived from intestinal microbiota and transported …

Background Progression of pancreatic ductal adenocarcinoma (PDAC) is largely the result
of genetic and/or epigenetic alterations in the transforming growth factor-beta (TGF-β)/Smad …

Introduction: In the last few years, several tyrosine kinase inhibitors (TKIs) have been
synthesized and become available for preclinical studies and clinical trials. This article …

Qingfei Paidu decoction (QFPD) has been repeatedly recommended for the clinical
treatment of novel coronavirus disease 2019 (COVID-19) in multiple provinces throughout …

Epithelial-mesenchymal transition (EMT) programs are essential in promoting breast cancer
invasion, systemic dissemination and in arousing proliferative programs in breast cancer …

The hallmark of pancreatic tumours, the desmoplastic reaction, provides a unique
microenvironment that affects pancreatic tumour behaviour, its ability to grow and …

Development of a physiologically relevant 3D model system for cancer research and drug
development is a current challenge. We have adopted a 3D culture system based on a …