Preterm birth and sustained inflammation: consequences for the neonate

A Humberg, I Fortmann, B Siller, MV Kopp… - Seminars in …, 2020 - Springer
Almost half of all preterm births are caused or triggered by an inflammatory process at the
feto-maternal interface resulting in preterm labor or rupture of membranes with or without …

Age, plasticity, and homeostasis in childhood brain disorders

M Dennis, BJ Spiegler, JJ Juranek, ED Bigler… - Neuroscience & …, 2013 - Elsevier
It has been widely accepted that the younger the age and/or immaturity of the organism, the
greater the brain plasticity, the young age plasticity privilege. This paper examines the …

Prenatal opioid exposure: the next neonatal neuroinflammatory disease

LL Jantzie, JR Maxwell, JC Newville… - Brain, behavior, and …, 2020 - Elsevier
The rates of opioid use disorder during pregnancy have more than quadrupled in the last
decade, resulting in numerous infants suffering exposure to opioids during the perinatal …

Improved relapse recovery in paediatric compared to adult multiple sclerosis

T Chitnis, G Aaen, A Belman, L Benson, M Gorman… - Brain, 2020 - academic.oup.com
Incomplete relapse recovery contributes to disability accrual and earlier onset of secondary
progressive multiple sclerosis. We sought to investigate the effect of age on relapse …

The young brain and concussion: imaging as a biomarker for diagnosis and prognosis

E Toledo, A Lebel, L Becerra, A Minster… - Neuroscience & …, 2012 - Elsevier
Concussion (mild traumatic brain injury (mTBI)) is a significant pediatric public health
concern. Despite increased awareness, a comprehensive understanding of the acute and …

Neuroimmune responses in the developing brain following traumatic brain injury

IW Nasr, Y Chun, S Kannan - Experimental neurology, 2019 - Elsevier
Traumatic brain injury (TBI) is one of the leading causes of both acute and long-term
morbidity in the pediatric population, leading to a substantial, long-term socioeconomic …

Pathophysiology of pediatric traumatic brain injury

RO Serpa, L Ferguson, C Larson, J Bailard… - Frontiers in …, 2021 - frontiersin.org
The national incidence of traumatic brain injury (TBI) exceeds that of any other disease in
the pediatric population. In the United States the Centers for Disease Control and Prevention …

Long-term effects of traumatic brain injury on anxiety-like behaviors in mice: behavioral and neural correlates

J Popovitz, SP Mysore, H Adwanikar - Frontiers in behavioral …, 2019 - frontiersin.org
Traumatic brain injury (TBI) has been frequently linked to affective disorders such as anxiety
and depression. However, much remains to be understood about the underlying molecular …

Angiopoietin/Tie2 axis regulates the age-at-injury cerebrovascular response to traumatic brain injury

TR Brickler, A Hazy, FG Correa, R Dai… - Journal of …, 2018 - Soc Neuroscience
Although age-at-injury influences chronic recovery from traumatic brain injury (TBI), the
differential effects of age on early outcome remain understudied. Using a male murine …

Contrasting pediatric and adult cerebral malaria: the role of the endothelial barrier

M Hawkes, RE Elphinstone, AL Conroy, KC Kain - Virulence, 2013 - Taylor & Francis
Malaria affects millions of people around the world and a small subset of those infected
develop cerebral malaria. The clinical presentation of cerebral malaria differs between …