The utilization of hydrogen by micro-organisms as a source of reducing power or of protons
as final electron acceptors is mediated by metalloenzymes called hydrogenases. The need …

Cytochrome c oxidase generates a proton motive force by two separate mechanisms. The
first mechanism is similar to that postulated by Peter Mitchell, and is based on electrons and …

A series of metalloprotein complexes embedded in a mitochondrial or bacterial membrane
utilize electron transfer reactions to pump protons across the membrane and create an …

Electron transfer in cell respiration is coupled to proton translocation across mitochondrial
and bacterial membranes, which is a primary event of biological energy transduction. The …

Advances in bioinorganic chemistry since the 1970s have been driven by three factors: rapid
determination of high-resolution structures of proteins and other biomolecules, utilization of …

Heme–copper oxidases (HCO), nitric oxide reductases (NOR), and sulfite reductases (SiR)
catalyze the multi-electron and multi-proton reductions of O2, NO, and SO32−, respectively …

Recent time-resolved optical and electrometric experiments have provided a sequence of
events for the proton-translocating mechanism of cytochrome c oxidase. These data also set …

Aerobic life is powered by membrane-bound redox enzymes that shuttle electrons to oxygen
and transfer protons across a biological membrane. Structural studies suggest that these …

Cytochrome c oxidase (CcO), as the terminal oxidase of cellular respiration, coupled with a
proton-pumping process, reduces molecular oxygen (O2) to water. This intriguing and highly …

Respiratory heme-copper oxidases are integral membrane proteins that catalyze the
reduction of molecular oxygen to water using electrons donated by either quinol (quinol …