British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

CA Lamb, NA Kennedy, T Raine, PA Hendy, PJ Smith… - Gut, 2019 - gut.bmj.com
Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

Current and emerging drugs for the treatment of inflammatory bowel disease

JK Triantafillidis, E Merikas… - … design, development and …, 2011 - Taylor & Francis
During the last decade a large number of biological agents against tumor necrosis factor-α
(TNF-α), as well as many biochemical substances and molecules specifically for the medical …

Efficacy of stem cells therapy for Crohn's fistula: a meta-analysis and systematic review

Y Cao, Q Su, B Zhang, F Shen, S Li - Stem cell research & therapy, 2021 - Springer
Background Fistulas have puzzled us all the time and stem cell therapy for it is still in its
infancy. We conducted a meta-analysis and systematic review to evaluate the efficacy of …

The benefits of pharmacogenetics for improving thiopurine therapy in inflammatory bowel disease

L Chouchana, C Narjoz, P Beaune… - Alimentary …, 2012 - Wiley Online Library
Aliment Pharmacol Ther 2012; 35: 15–36 Summary Background Thiopurines represent an
effective and widely prescribed therapy in inflammatory bowel disease (IBD). Concerns …

Thiopurines in inflammatory bowel disease: new findings and perspectives

NKH de Boer, L Peyrin-Biroulet, B Jharap… - Journal of Crohn's …, 2018 - academic.oup.com
Thiopurines, available as azathioprine, mercaptopurine, and thioguanine, are
immunomodulating agents primarily used to maintain corticosteroid-free remission in …

British Association of Dermatologists' guidelines for the safe and effective prescribing of azathioprine 2011

SJ Meggitt, AV Anstey… - British Journal of …, 2011 - academic.oup.com
Azathioprine is a thiopurine immunosuppressant drug that occupies an important place in
the management of many autoimmune and inflammatory skin diseases. Its parent drug 6 …

Recent advances in pharmacogenetics and pharmacokinetics for safe and effective thiopurine therapy in inflammatory bowel disease

W Moon, EV Loftus Jr - Alimentary pharmacology & therapeutics, 2016 - Wiley Online Library
Background Azathioprine and mercaptopurine have a pivotal role in the treatment of
inflammatory bowel disease (IBD). However, because of their complex metabolism and …

Inflammatory bowel disease of the elderly: frequently asked questions (FAQs)

S Katz, DS Pardi - Official journal of the American College of …, 2011 - journals.lww.com
The growing recognition of the older inflammatory bowel disease (IBD) patient is heightened
by the entry of the 77.2 million baby boomers who will turn 65 beginning of 2011. It is …

A practical guide to thiopurine prescribing and monitoring in IBD

B Warner, E Johnston, M Arenas-Hernandez… - Frontline …, 2018 - fg.bmj.com
Thiopurines are often the mainstay of treatment for many patients with inflammatory bowel
disease. As such, a general understanding of the evidence behind their use and of their …

Revisiting the role of thiopurines in inflammatory bowel disease through pharmacogenomics and use of novel methods for therapeutic drug monitoring

SZ Lim, EW Chua - Frontiers in pharmacology, 2018 - frontiersin.org
Azathioprine and 6-mercaptopurine, often referred to as thiopurine compounds, are
commonly used in the management of inflammatory bowel disease. However, patients …