Technetium-99m radiopharmaceuticals for ideal myocardial perfusion imaging: lost and found opportunities

A Boschi, L Uccelli, L Marvelli, C Cittanti, M Giganti… - Molecules, 2022 - mdpi.com
The favorable nuclear properties in combination with the rich coordination chemistry make
technetium-99m the radioisotope of choice for the development of myocardial perfusion …

Technetium (I) carbonyl complexes for nuclear medicine: Coordination-chemical aspect

GV Sidorenko, AE Miroslavov, MY Tyupina - Coordination Chemistry …, 2023 - Elsevier
Studies concerning the development of radiopharmaceuticals based on the Tc (I) carbonyl
core are considered from the coordination-chemical viewpoint. The coordination behavior of …

Organometallic complexes for SPECT imaging and/or radionuclide therapy

GR Morais, A Paulo, I Santos - Organometallics, 2012 - ACS Publications
This article reviews Re and Tc organometallic chemistry and radiochemistry, focusing on the
most relevant aspects to design radiotools for molecular imaging and therapy. The review …

Novel polar single amino acid chelates for technetium-99m tricarbonyl-based radiopharmaceuticals with enhanced renal clearance: application to octreotide

KP Maresca, JC Marquis, SM Hillier, G Lu… - Bioconjugate …, 2010 - ACS Publications
Single amino acid chelate (SAAC) systems for the incorporation of the M (CO) 3 moiety (M=
Tc/Re) have been successfully incorporated into novel synthetic strategies for …

Golden jubilee for scorpionates: Recent advances in organometallic chemistry and their role in catalysis

C Pettinari, R Pettinari, F Marchetti - Advances in Organometallic Chemistry, 2016 - Elsevier
This review aims to describe some recent trends in organometallic complexes containing
scorpionate ligands. Particular attention will be paid to the ligands structure, reagents, and …

New Ga derivatives of the H2dedpa scaffold with improved clearance and persistent heart uptake

E Boros, CL Ferreira, BO Patrick, MJ Adam… - Nuclear medicine and …, 2011 - Elsevier
Recent advances in positron emission tomography (PET)/computed tomography have
fueled the development of new PET-isotope-based agents for myocardial perfusion imaging …

Rhenium and technetium complexes with anionic or neutral scorpionates: An overview of their relevance in biomedical applications

R Garcia, A Paulo, I Santos - Inorganica Chimica Acta, 2009 - Elsevier
This article reviews the chemistry of Re and Tc complexes anchored by anionic and neutral
scorpionates with potential relevance in the field of biomedical applications, particularly in …

Metal complexes of tridentate tripod ligands in medical imaging and therapy

F Silva, C Fernandes, MPC Campello, A Paulo - Polyhedron, 2017 - Elsevier
Since their development in the late 1960s, scorpionate ligands have played a great part in
the design of novel compounds in the field of coordination chemistry. In this review we focus …

Technetium complexes and radiopharmaceuticals with scorpionate ligands

P Martini, M Pasquali, A Boschi, L Uccelli, M Giganti… - Molecules, 2018 - mdpi.com
Scorpionate ligands have played a crucial role in the development of technetium chemistry
and, recently, they have also fueled important advancements in the discovery of novel …

99mTc: Labeling Chemistry and Labeled Compounds

R Alberto, U Abram - Handbook of nuclear chemistry, 2011 - ui.adsabs.harvard.edu
This chapter reviews the radiopharmaceutical chemistry of technetium related to the
synthesis of perfusion agents and to the labeling of receptor-binding biomolecules. To …