Endolysins are bacteriophage-encoded enzymes that can specifically degrade the
peptidoglycan layer of bacterial cell wall, making them an attractive tool for the development …

One of the last untapped reservoirs in nature for the identification of new anti-microbials is
bacteriophages, the natural killers of bacteria. Lytic bacteriophages encode peptidoglycan …

Bacteriophage‐encoded endolysins can recognize and bind specific bacteria, and act to
cleave the glycosidic and/or amide bonds in the peptidoglycan (PG) bacterial cell wall …

D29 mycobacteriophage encodes LysA endolysin, which mediates mycobacterial host cell
lysis by targeting its peptidoglycan layer, thus projecting itself as a potential therapeutic …

Mycobacteriophages are viruses that specifically infect mycobacteria, which ultimately
culminate in host cell death. Dedicated enzymes targeting the complex mycobacterial cell …

In light of emerging antibiotic resistance, bacterial cell wall lytic enzymes are promising
antimicrobial agents that degrade bacterial peptidoglycan while specifically recognizing the …

Holins are phage‐encoded small transmembrane proteins that perforate the bacterial
cytoplasmic membrane. In most cases, this process allows the phage‐encoded …

Endolysins (lysins) are bacteriophage-encoded enzymes that have evolved to degrade
specific bonds within the bacterial cell wall. These enzymes represent a novel class of …

Streptococcus pneumoniae is highly pathogenic and causes several mucosal and invasive
infections. Due to the rising number of multidrug-resistant (MDR) strains of S. pneumoniae …

Antibiotics are the molecules of choice to treat bacterial infections. However, because of the
rapid emergence of drug-resistant bacteria, alternative modes of combating infections are …