[HTML][HTML] Mannan-Decorated Lipid Calcium Phosphate Nanoparticle Vaccine Increased the Antitumor Immune Response by Modulating the Tumor Microenvironment
L Wu, L Yang, X Qian, W Hu, S Wang… - Journal of Functional …, 2024 - mdpi.com
With the rapid development of tumor immunotherapy, nanoparticle vaccines have attracted
much attention as potential therapeutic strategies. A systematic review and analysis must be …
much attention as potential therapeutic strategies. A systematic review and analysis must be …
Ecological and evolutionary challenges for wildlife vaccination
KM Barnett, DJ Civitello - Trends in Parasitology, 2020 - cell.com
Wildlife vaccination is of urgent interest to reduce disease-induced extinction and zoonotic
spillover events. However, several challenges complicate its application to wildlife. For …
spillover events. However, several challenges complicate its application to wildlife. For …
A transmissible cancer shifts from emergence to endemism in Tasmanian devils
INTRODUCTION Emerging infectious diseases pose one of the greatest threats to human
health and biodiversity. Phylodynamics is an effective tool for inferring epidemiological …
health and biodiversity. Phylodynamics is an effective tool for inferring epidemiological …
Applied ecoimmunology: using immunological tools to improve conservation efforts in a changing world
Ecoimmunology is a rapidly developing field that explores how the environment shapes
immune function, which in turn influences host–parasite relationships and disease …
immune function, which in turn influences host–parasite relationships and disease …
[HTML][HTML] Update on lyssaviruses and rabies: will past progress play as prologue in the near term towards future elimination?
RE Rohde, CE Rupprecht - Faculty reviews, 2020 - ncbi.nlm.nih.gov
Rabies is an ancient, much-feared, and neglected infectious disease. Caused by pathogens
in the family Rhabdoviridae, genus Lyssavirus, and distributed globally, this viral zoonosis …
in the family Rhabdoviridae, genus Lyssavirus, and distributed globally, this viral zoonosis …
NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in transmissible cancers
Purpose Downregulation of MHC class I (MHC-I) is a common immune evasion strategy of
many cancers. Similarly, two allogeneic clonal transmissible cancers have killed thousands …
many cancers. Similarly, two allogeneic clonal transmissible cancers have killed thousands …
[HTML][HTML] Saving the Devils is in the details: Tasmanian Devil facial tumor disease can be eliminated with interventions
Tasmanian Devils facial tumor disease (DFTD) is severely impacting the population of this
wild animal. We developed a computational model of the population of Tasmanian Devils …
wild animal. We developed a computational model of the population of Tasmanian Devils …
A novel system to map protein interactions reveals evolutionarily conserved immune evasion pathways on transmissible cancers
Around 40% of humans and Tasmanian devils (Sarcophilus harrisii) develop cancer in their
lifetime, compared to less than 10% for most species. In addition, devils are affected by two …
lifetime, compared to less than 10% for most species. In addition, devils are affected by two …
A human adenovirus encoding IFN-γ can transduce Tasmanian devil facial tumour cells and upregulate MHC-I
AN Kayigwe, J M. Darby, AB Lyons… - Journal of General …, 2022 - microbiologyresearch.org
The devil facial tumour disease (DFTD) has led to a massive decline in the wild Tasmanian
devil (Sarcophilus harrisii) population. The disease is caused by two independent devil …
devil (Sarcophilus harrisii) population. The disease is caused by two independent devil …
Post-release immune responses of Tasmanian devils vaccinated with an experimental devil facial tumour disease vaccine
AbstractContext Disease is increasingly becoming a driver of wildlife population declines
and an extinction risk. Vaccines are one of the most successful health interventions in …
and an extinction risk. Vaccines are one of the most successful health interventions in …