[HTML][HTML] Targeting iron metabolism in cancer therapy

M Morales, X Xue - Theranostics, 2021 - ncbi.nlm.nih.gov
Iron is a critical component of many cellular functions including DNA replication and repair,
and it is essential for cell vitality. As an essential element, iron is critical for maintaining …

The application of ferroptosis in diseases

Y Qiu, Y Cao, W Cao, Y Jia, N Lu - Pharmacological Research, 2020 - Elsevier
Ferroptosis is a new kind of regulated cell death that is characterized by highly iron-
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …

[HTML][HTML] Current understanding of iron homeostasis

GJ Anderson, DM Frazer - The American journal of clinical nutrition, 2017 - Elsevier
Iron is an essential trace element, but it is also toxic in excess, and thus mammals have
developed elegant mechanisms for keeping both cellular and whole-body iron …

The importance of minerals in human nutrition: Bioavailability, food fortification, processing effects and nanoencapsulation

SMT Gharibzahedi, SM Jafari - Trends in Food Science & Technology, 2017 - Elsevier
Background As minerals have diverse functionalities and potentials in the body's
metabolism and homeostasis, deficiency of these bioactive constituents can result in an …

[HTML][HTML] Biomarkers of Nutrition for Development (BOND)—iron review

S Lynch, CM Pfeiffer, MK Georgieff, G Brittenham… - The Journal of …, 2018 - Elsevier
This is the fifth in the series of reviews developed as part of the Biomarkers of Nutrition for
Development (BOND) program. The BOND Iron Expert Panel (I-EP) reviewed the extant …

Correlation between in vitro and in vivo data on food digestion. What can we predict with static in vitro digestion models?

T Bohn, F Carriere, L Day, A Deglaire… - Critical reviews in …, 2018 - Taylor & Francis
During the last decade, there has been a growing interest in understanding food's digestive
fate in order to strengthen the possible effects of food on human health. Ideally, food …

Association between obesity and iron deficiency

NM Alshwaiyat, A Ahmad… - Experimental and …, 2021 - spandidos-publications.com
Obesity is a risk factor for several comorbidities and complications, including iron deficiency
anemia. Iron deficiency anemia is a serious global public health problem, with a worldwide …

Iron metabolism in the CNS: implications for neurodegenerative diseases

TA Rouault - Nature Reviews Neuroscience, 2013 - nature.com
Abnormal accumulation of brain iron has been detected in various neurodegenerative
diseases, but the contribution of iron overload to pathology remains unclear. In a group of …

The dark side of iron: the relationship between iron, inflammation and gut microbiota in selected diseases associated with iron deficiency anaemia—a narrative review

IJ Malesza, J Bartkowiak-Wieczorek, J Winkler-Galicki… - Nutrients, 2022 - mdpi.com
Iron is an indispensable nutrient for life. A lack of it leads to iron deficiency anaemia (IDA),
which currently affects about 1.2 billion people worldwide. The primary means of IDA …

Barriers impairing mineral bioaccessibility and bioavailability in plant-based foods and the perspectives for food processing

S Rousseau, C Kyomugasho, M Celus… - Critical Reviews in …, 2020 - Taylor & Francis
Plant-based foods gain more importance since they play a key role in sustainable, low-meat
and healthy diets. In developing countries, these food products, especially legumes and …