S-nitrosylation, the covalent attachment of a nitrogen monoxide group to the thiol side chain of cysteine, has emerged as an important mechanism for dynamic, post-translational …
S Lee, SM Kim, RT Lee - Antioxidants & redox signaling, 2013 - liebertpub.com
The thioredoxin (Trx) system is one of the central antioxidant systems in mammalian cells, maintaining a reducing environment by catalyzing electron flux from nicotinamide adenine …
T Nakamura, S Tu, MW Akhtar, CR Sunico, S Okamoto… - Neuron, 2013 - cell.com
S-Nitrosylation is a redox-mediated posttranslational modification that regulates protein function via covalent reaction of nitric oxide (NO)-related species with a cysteine thiol group …
JA McCubrey, MM LaHair… - Antioxidants & redox …, 2006 - liebertpub.com
An abundance of scientific literature exists demonstrating that oxidative stress influences the MAPK signaling pathways. This review summarizes these findings for the ERK, JNK, p38 …
Protein post-translational modification by S-nitrosylation conveys a ubiquitous influence of nitric oxide on signal transduction in eukaryotic cells. The wide functional purview of S …
A Corcoran, TG Cotter - The FEBS journal, 2013 - Wiley Online Library
Reactive oxygen species (ROS) have been long regarded as by‐products of a cascade of reactions stemming from cellular oxygen metabolism, which, if they accumulate to toxic …
HM Shen, Z Liu - Free Radical Biology and Medicine, 2006 - Elsevier
c-Jun N-terminal kinase (JNK), or stress-activated protein kinase, is an important member of the mitogen-activated protein kinase superfamily, the members of which are readily …
A Lin, Y Wang, J Tang, P Xue, C Li, L Liu, B Hu… - Plant …, 2012 - academic.oup.com
Nitric oxide (NO) is a key redox-active, small molecule involved in various aspects of plant growth and development. Here, we report the identification of an NO accumulation mutant …
S Mocellin, V Bronte, D Nitti - Medicinal research reviews, 2007 - Wiley Online Library
Nitric oxide (NO) is a pleiotropic molecule critical to a number of physiological and pathological processes. The last decade has witnessed major advances in dissecting NO …