ATP synthase is a ubiquitous enzyme that is largely conserved across the kingdoms of life.
This conservation is in accordance with its central role in chemiosmotic energy conversion, a …

For decades, proteins were thought to be the sole or at least the dominant source of
antigens for T cells. Studies in the 1990s demonstrated that CD 1 proteins and …

Control and manipulation of bacterial populations requires an understanding of the factors
that govern growth, division, and antibiotic action. Fluorescent and chemically reactive small …

The twin-arginine protein translocation (Tat) system has a unique ability to translocate folded
and co-factor-containing proteins across lipid bilayers. The Tat pathway is present in …

Actinobacteria is a group of diverse bacteria. Most species in this class of bacteria are
filamentous aerobes found in soil, including the genus Streptomyces perhaps best known for …

The antimicrobial properties of garlic are widely known, and numerous studies confirmed its
ability to inhibit the growth of Mycobacterium tuberculosis. In this work, we explored the …

Introduction Pulmonary tuberculosis (TB) is a major worldwide health problem that lacks
robust blood-based biomarkers for detection of active disease. High-resolution …

The highly adaptive cellular response of Mycobacterium tuberculosis to various antibiotics
and the high costs for clinical trials, hampers the development of novel antimicrobial agents …

All mycobacteria, including nontuberculous mycobacteria (NTM), synthesize an array of
lipids including phosphatidylinositol mannosides (PIM), lipomannan (LM), and …

Propolis is a natural product proved to be efficient against Mycobacterium tuberculosis.
Although it is produced by bees, its active alcoholic-aqueous fraction contains plant-derived …